Pharmacokinetics of and maintenance dose recommendations for vancomycin in severe pneumonia patients undergoing continuous venovenous hemofiltration with the combination of predilution and postdilution
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DOI: 10.1007/s00228-019-02755-5
Abstract: Purpose Therapeutic vancomycin levels are difficult to maintain in severe pneumonia patients who are receiving IV vancomycin therapy while on continuous venovenous hemofiltration (CVVH). The objective of this study was to determine the pharmacokinetics and… read more here.
Keywords: vancomycin severe; maintenance dose; pneumonia patients; severe pneumonia ... See more keywords
Use of the VerifyNow point of care assay to assess the pharmacodynamic effects of loading and maintenance dose regimens of prasugrel and ticagrelor
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DOI: 10.1007/s11239-021-02386-7
Abstract: Prasugrel and ticagrelor are potent oral platelet P2Y12 inhibitors and are recommended over clopidogrel in patients with acute coronary syndrome (ACS). Oral platelet P2Y12 inhibitors are characterized by varying degrees of pharmacodynamic response profiles as… read more here.
Keywords: use; maintenance dose; ticagrelor; prasugrel ticagrelor ... See more keywords
Evaluation of the Pharmacokinetics and Pharmacodynamics of Prasugrel in Japanese Elderly Subjects
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DOI: 10.1007/s40261-017-0525-0
Abstract: Background and ObjectiveAn increased incidence in bleeding events has been reported in Western elderly patients receiving prasugrel. Therefore, doses in Japanese elderly subjects need to be carefully determined. We assessed the pharmacokinetic and pharmacodynamic effects… read more here.
Keywords: plasma concentration; elderly subjects; maintenance dose; japanese elderly ... See more keywords
Influence of titration schedule and maintenance dose on the tolerability of adjunctive eslicarbazepine acetate: An integrated analysis of three randomized placebo-controlled trials
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DOI: 10.1016/j.eplepsyres.2017.10.021
Abstract: OBJECTIVE To examine the influence of titration schedule and maintenance dose on the incidence and type of treatment-emergent adverse events (TEAEs) associated with adjunctive eslicarbazepine acetate (ESL). METHODS Data from three randomized, double-blind, placebo-controlled trials… read more here.
Keywords: titration; maintenance dose; maintenance; placebo ... See more keywords
Serum magnesium levels during magnesium sulfate infusion at 1 gram/hour versus 2 grams/hour as a maintenance dose to prevent eclampsia in women with severe preeclampsia
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DOI: 10.1097/md.0000000000016779
Abstract: Abstract Background: Magnesium sulfate is the ideal drug for the prevention and treatment of eclampsia. Nevertheless, the best regimen for protection against eclampsia with minimal side effects remains to be established. This study aimed to… read more here.
Keywords: magnesium sulfate; maintenance dose; gram hour; hour ... See more keywords
Impact of VKORC1, CYP2C9, CYP1A2, UGT1A1, and GGCX polymorphisms on warfarin maintenance dose: Exploring a new algorithm in South Chinese patients accept mechanical heart valve replacement
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DOI: 10.1097/md.0000000000029626
Abstract: Background: Warfarin is the most recommended oral anticoagulant after artificial mechanical valve replacement therapy. However, the narrow therapeutic window and varying safety and efficacy in individuals make dose determination difficult. It may cause adverse events… read more here.
Keywords: maintenance dose; valve replacement; dose; ggcx ... See more keywords
Effectiveness, safety, initial optimal dose, and optimal maintenance dose range of basal insulin regimens for type 2 diabetes: A systematic review with meta‐analysis
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DOI: 10.1111/1753-0407.13381
Abstract: To investigate the effectiveness, safety, optimal starting dose, optimal maintenance dose range, and target fasting plasma glucose of five basal insulins in insulin‐naïve patients with type 2 diabetes mellitus. read more here.
Keywords: maintenance dose; dose; dose optimal; effectiveness safety ... See more keywords
Immunologic changes after house dust mite modified rush subcutaneous immunotherapy in allergic rhinitis children
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DOI: 10.5415/apallergy.2022.12.e4
Abstract: Background House dust mites (HDM) are the major causative allergen for allergic rhinitis. The sole disease-modifying therapy for allergic rhinitis is allergen immunotherapy (AIT). Rush immunotherapy is the accelerated build-up schedules to reach the target… read more here.
Keywords: maintenance dose; modified rush; rhinitis; allergic rhinitis ... See more keywords