Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-81129-3
Abstract: Patient-derived cellular models become an increasingly powerful tool to model human diseases for precision medicine approaches. The identification of robust cellular disease phenotypes in these models paved the way towards high throughput screenings (HTS) including… read more here.
Keywords: maintenance expansion; expansion; derived cellular; cellular models ... See more keywords
Maintenance and expansion of genetic and trait variation following domestication in a clonal crop.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular ecology"
DOI: 10.1111/mec.17033
Abstract: Clonal propagation enables favourable crop genotypes to be rapidly selected and multiplied. However, the absence of sexual propagation can lead to low genetic diversity and accumulation of deleterious mutations, which may eventually render crops less… read more here.
Keywords: domestication; crop; clonal propagation; maintenance expansion ... See more keywords