Benzimidazole inhibitors of the major cysteine protease of Trypanosoma brucei.
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DOI: 10.4155/fmc-2018-0523
Abstract: Aim: Limitations in available therapies for trypanosomiases indicate the need for improved medicines. Cysteine proteases cruzain and rhodesain are validated targets for treatment of Chagas disease and human African trypanosomiasis. Previous studies reported a benzimidazole… read more here.
Keywords: brucei; major cysteine; trypanosoma brucei; benzimidazole inhibitors ... See more keywords