Variations in the frequencies of polymorphisms in the CYP2C9 gene in six major ethnicities of Pakistan
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-76366-x
Abstract: Genetic variation in cytochrome P450 (CYP) 2C9 is known to cause significant inter-individual differences in drug response and adverse effects. The frequencies of CYP2C9*2 and CYP2C9*3, both of which are responsible for the low activity… read more here.
Keywords: low activity; major ethnicities; ethnicities pakistan; activity ... See more keywords
Variations in the Frequencies of Polymorphisms in the CYP450s Genes in Eight Major Ethnicities of Iran: A Review of the Human Data
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12111848
Abstract: Genetic polymorphisms in cytochrome P450 genes can cause variation in metabolism. Thus, single nucleotide variants significantly impact drug pharmacokinetics, toxicity factors, and efficacy and safety of medicines. The distribution of CYP450 alleles varies drastically across… read more here.
Keywords: frequencies polymorphisms; variations frequencies; major ethnicities; ethnicities iran ... See more keywords