Liver hypertrophy: Underlying mechanisms and promoting procedures before major hepatectomy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of visceral surgery"
DOI: 10.1016/j.jviscsurg.2018.03.005
Abstract: Various procedures can promote hypertrophy of the future liver remnant (FLR) before major hepatectomy to prevent postoperative liver failure. The pathophysiological situation following portal vein embolization (PVE), hepatic artery ligation/embolization or hepatectomy remains unclear. On… read more here.
Keywords: hepatectomy; regeneration; liver; embolization ... See more keywords
Fatty liver: The metabolic syndrome increases major hepatectomy mortality.
Sign Up to like & getrecommendations! Published in 2020 at "Surgery"
DOI: 10.1016/j.surg.2020.11.021
Abstract: BACKGROUND As the obesity epidemic worsens, the prevalence of fatty liver disease has increased. However, minimal data exist on the impact of combined fatty liver and metabolic syndrome on hepatectomy outcomes. Therefore, the aim of… read more here.
Keywords: fatty liver; patients fatty; mortality; metabolic syndrome ... See more keywords
Perioperative treatment with cilostazol reverses steatosis and improves liver regeneration after major hepatectomy in a steatotic rat model
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-87135-z
Abstract: Cilostazol has previously been shown to reduce liver steatosis and enhance hepatic perfusion. We investigated the effects of cilostazol after major hepatectomy in a steatotic rat model. Six weeks prior to surgery, Sprague–Dawley rats were… read more here.
Keywords: treatment; cilostazol; group; hepatectomy steatotic ... See more keywords
Hepatocellular uptake index obtained with gadoxetate disodium-enhanced magnetic resonance imaging in the assessment future liver remnant function after major hepatectomy for biliary malignancy
Sign Up to like & getrecommendations! Published in 2021 at "BJS Open"
DOI: 10.1093/bjsopen/zraa048
Abstract: Abstract Background Functional assessment of the future liver remnant (FLR) after major hepatectomy is essential but often difficult in patients with biliary malignancy, owing to obstructive jaundice and portal vein embolization. This study evaluated whether… read more here.
Keywords: hepatectomy biliary; index; major hepatectomy; biliary malignancy ... See more keywords
Impact of post-hepatectomy liver failure on morbidity and short- and long-term survival after major hepatectomy
Sign Up to like & getrecommendations! Published in 2022 at "BJS Open"
DOI: 10.1093/bjsopen/zrac097
Abstract: Abstract Background Post-hepatectomy liver failure (PHLF) is one of the most serious postoperative complications after hepatectomy. The aim of this study was to assess the impact of the International Study Group of Liver Surgery (ISGLS)… read more here.
Keywords: long term; major hepatectomy; hepatectomy; term survival ... See more keywords
De Novo Endotoxin-Induced Production of Antibodies against the Bile Salt Export Pump Associated with Bacterial Infection following Major Hepatectomy
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/6197152
Abstract: Background Clinically severe infection-related inflammation after major liver resection may cause hyperbilirubinemia. This study aims to clarify the impact of bacterial infection and endotoxins on the hepatobiliary transporter system and to explore possible mechanisms of… read more here.
Keywords: bile salt; infection; bacterial infection; major hepatectomy ... See more keywords
Association between the Achievement of Textbook Outcomes in Liver Surgery and Overall Survival in Perihilar Cholangiocarcinoma Patients following Major Hepatectomy: A Multicenter Study
Sign Up to like & getrecommendations! Published in 2025 at "Digestive Diseases"
DOI: 10.1159/000543439
Abstract: Abstract Introduction: Major hepatectomy is the mainstay of curative-intent resection for perihilar cholangiocarcinoma (pCCA) patients. Textbook outcomes in liver surgery (TOLS) are a new composite parameter for evaluating the short-term outcomes of surgery; however, their… read more here.
Keywords: following major; pcca patients; study; major hepatectomy ... See more keywords
Deep learning for fully automated segmentation and volumetry of Couinaud liver segments and future liver remnants shown with CT before major hepatectomy: a validation study of a predictive model
Sign Up to like & getrecommendations! Published in 2023 at "Quantitative Imaging in Medicine and Surgery"
DOI: 10.21037/qims-22-1008
Abstract: Background Recent reports have shown the potential for deep learning (DL) models to automatically segment of Couinaud liver segments and future liver remnant (FLR) for liver resections. However, these studies have mainly focused on the… read more here.
Keywords: major hepatectomy; liver; couinaud liver; segmentation ... See more keywords
Bevacizumab Does Not Inhibit the Formation of Liver Vessels and Liver Regeneration Following Major Hepatectomy: A Large Animal Model Study
Sign Up to like & getrecommendations! Published in 2022 at "In Vivo"
DOI: 10.21873/invivo.12806
Abstract: Background/Aim: Patients with unresectable liver colorectal cancer metastases are treated with neoadjuvant chemotherapy often accompanied by biological therapy aimed at reducing the mass of metastases and thus increasing the chances of resectability. Bevacizumab comprises an… read more here.
Keywords: regeneration; major hepatectomy; liver; large animal ... See more keywords
Perioperative Oral β-Hydroxy-β-Methylbutyrate Supplementation Ameliorates Sarcopenia in Rats Undergoing Major Hepatectomy.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of nutritional science and vitaminology"
DOI: 10.3177/jnsv.68.276
Abstract: β-Hydroxy-β-methylbutyrate (HMB), a metabolite of leucine, is known to increase muscle mass and strength. However, the effect of perioperative HMB supplementation in liver surgery is unclear. Moreover, the impact of HMB on the skeletal muscle… read more here.
Keywords: hmb; major hepatectomy; body composition; rats undergoing ... See more keywords
A Novel Nomogram for Predicting Postoperative Liver Failure After Major Hepatectomy for Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.817895
Abstract: Background Post-hepatectomy liver failure (PHLF) is the most common cause of mortality after major hepatectomy in hepatocellular carcinoma (HCC) patients. We aim to develop a nomogram to preoperatively predict grade B/C PHLF defined by the… read more here.
Keywords: major hepatectomy; hepatocellular carcinoma; liver failure; hepatectomy hepatocellular ... See more keywords