Etizolam and Its Major Metabolites: A Short Review.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkac096
Abstract: Etizolam is a benzodiazepine (BZD). Etizolam is structurally different from BZDs as a thiophene replaces the benzene ring, and a triazole ring is fused to the diazepine ring, but etizolam's pharmacological profile is similar. Etizolam… read more here.
Keywords: toxicology; review; etizolam major; metabolites short ... See more keywords
Residue depletion of amoxicillin and its major metabolites in eggs
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Veterinary Pharmacology and Therapeutics"
DOI: 10.1111/jvp.12363
Abstract: The depletion of amoxicillin (AMO) and its major metabolites, amoxicilloic acid (AMA) and amoxicillin-diketopiperazine-2',5'-dione (DIKETO) in the albumen, yolk and whole egg was studied after the oral dose of AMO (25 and 50 mg/kg body weight)… read more here.
Keywords: amoxicillin major; residue depletion; diketo; depletion amoxicillin ... See more keywords
Validated liquid chromatography coupled to tandem mass spectrometry method for simultaneous quantitation of tolvaptan and its five major metabolites in human plasma
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical Biochemistry"
DOI: 10.1177/0004563219827045
Abstract: Background Tolvaptan is converted to major metabolites including three monohydroxylates (DM-4110, DM-4111 and DM-4119), an oxidate (MOP-21826) and a carboxylate (DM-4103) in humans. This study developed a simultaneous quantitative method for tolvaptan and its five… read more here.
Keywords: plasma; method; tolvaptan five; metabolites human ... See more keywords
Cardiovascular Effects of Polychlorinated Biphenyls and Their Major Metabolites
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DOI: 10.1289/ehp7030
Abstract: Background: Xenobiotic metabolism is complex, and accounting for bioactivation and detoxification processes of chemicals remains among the most challenging aspects for decision making with in vitro new approach methods data. Objectives: Considering the physiological relevance… read more here.
Keywords: major metabolites; pcbs; effects polychlorinated; polychlorinated biphenyls ... See more keywords
Pharmacokinetics, Tissue Distribution and Excretion of Paeonol and Its Major Metabolites in Rats Provide a Further Insight Into Paeonol Effectiveness
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.00190
Abstract: Paeonol is a major bioactive ingredient in Moutan Cortex (the root barks of Paeonia suffruticosa Andrews) and exhibited a wide range of bioactivities such as anti-inflammation, anti-oxidation, hypoglycemic effect, analgesic, and others. Even though paeonol… read more here.
Keywords: excretion; paeonol; paeonol major; pharmacokinetics tissue ... See more keywords