Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2023.1137
Abstract: Importance Premenstrual disorders are heritable, clinically heterogenous, with a range of affective spectrum comorbidities. It is unclear whether genetic predispositions to affective spectrum disorders or other major psychiatric disorders are associated with symptoms of premenstrual… read more here.
Keywords: major psychiatric; psychiatric disorders; premenstrual disorders; liability ... See more keywords
Glial Cell Abnormalities in Major Psychiatric Diseases: A Systematic Review of Postmortem Brain Studies.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular neurobiology"
DOI: 10.1007/s12035-021-02672-8
Abstract: There have been a large number of reports about glial cell dysfunction being related to major psychiatric diseases such as schizophrenia (SCZ), bipolar disorder (BD), and major depressive disorder (MDD). In this review, we provide… read more here.
Keywords: major psychiatric; review; psychiatric diseases; glial cell ... See more keywords
T46 In Vitro Human Neuronal Differentiation Validated As Genomic Model System To Study Major Psychiatric Illnesses
Sign Up to like & getrecommendations! Published in 2017 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2016.09.534
Abstract: Background Large-scale genetic studies of neuropsychiatric disorders have identified hundreds of susceptibility alleles. An important next challenge is to understand how identified genetic risk loci impact biological pathways and disease. For this, model systems are… read more here.
Keywords: psychiatric illnesses; major psychiatric; disease; model ... See more keywords
[Prevalence of Hypothyroidism in Major Psychiatric Disorders in Hospitalised Patients in Montserrat Hospital During the period March to October 2010].
Sign Up to like & getrecommendations! Published in 2017 at "Revista colombiana de psiquiatria"
DOI: 10.1016/j.rcp.2016.06.006
Abstract: INTRODUCTION Hypothyroidism results from inadequate production of thyroid hormone. It is known that there is a relationship between the major psychiatric disorders and hypothyroidism. OBJECTIVE To determine the prevalence of hypothyroidism in patients admitted due… read more here.
Keywords: hypothyroidism; major psychiatric; disorder; psychiatric disorders ... See more keywords
Investigating the neurobiology of schizophrenia and other major psychiatric disorders with Transcranial Magnetic Stimulation
Sign Up to like & getrecommendations! Published in 2018 at "Schizophrenia Research"
DOI: 10.1016/j.schres.2017.04.045
Abstract: Characterizing the neurobiology of schizophrenia and other major psychiatric disorders is one of the main challenges of the current research in psychiatry. The availability of Transcranial Magnetic Stimulation (TMS) allows to directly probe virtually any… read more here.
Keywords: schizophrenia; psychiatric disorders; major psychiatric; schizophrenia major ... See more keywords
The joint impact of cognitive performance in adolescence and familial cognitive aptitude on risk for major psychiatric disorders: a delineation of four potential pathways to illness
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Psychiatry"
DOI: 10.1038/mp.2017.78
Abstract: How do joint measures of premorbid cognitive ability and familial cognitive aptitude (FCA) reflect risk for a diversity of psychiatric and substance use disorders? To address this question, we examined, using Cox models, the predictive… read more here.
Keywords: risk; major psychiatric; fca; familial cognitive ... See more keywords
Applying dimensional psychopathology: transdiagnostic associations among regional homogeneity, leptin and depressive symptoms
Sign Up to like & getrecommendations! Published in 2020 at "Translational Psychiatry"
DOI: 10.1038/s41398-020-00932-0
Abstract: Dimensional psychopathology and its neurobiological underpinnings could provide important insights into major psychiatric disorders, including major depressive disorder, bipolar disorder and schizophrenia. In a dimensional transdiagnostic approach, we examined depressive symptoms and their relationships with… read more here.
Keywords: depressive symptoms; major psychiatric; psychiatric disorders; regional homogeneity ... See more keywords
Lifespan Gyrification Trajectories of Human Brain in Healthy Individuals and Patients with Major Psychiatric Disorders
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-00582-1
Abstract: Cortical gyrification of the brain represents the folding characteristic of the cerebral cortex. How the brain cortical gyrification changes from childhood to old age in healthy human subjects is still unclear. Additionally, studies have shown… read more here.
Keywords: gyrification trajectories; major psychiatric; psychiatric disorders; gyrification ... See more keywords
Assessing the Causal Effects of Human Serum Metabolites on 5 Major Psychiatric Disorders.
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia bulletin"
DOI: 10.1093/schbul/sbz138
Abstract: Psychiatric disorders are the leading cause of disability worldwide while the pathogenesis remains unclear. Genome-wide association studies (GWASs) have made great achievements in detecting disease-related genetic variants. However, functional information on the underlying biological processes… read more here.
Keywords: serum metabolites; psychiatric disorders; metabolites major; major psychiatric ... See more keywords
Offspring outcomes when a parent experiences one or more major psychiatric disorder(s): a clinical review
Sign Up to like & getrecommendations! Published in 2020 at "Evidence-Based Mental Health"
DOI: 10.1136/ebmental-2019-300123
Abstract: We sought evidence on quantifiable offspring outcomes, including problems, needs and strengths, associated with their experience of major parental psychiatric disorder(s), focusing on schizophrenia, affective illnesses and personality disorder(s). We were motivated by the absence… read more here.
Keywords: outcomes parent; major psychiatric; disorder; psychiatric disorder ... See more keywords
A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1008185
Abstract: Psychiatric disorders are highly heritable and associated with a wide variety of social adversity and physical health problems. Using genetic liability (rather than phenotypic measures of disease) as a proxy for psychiatric disease risk can… read more here.
Keywords: prs phewas; cross disorder; psychiatric disorders; disorder ... See more keywords