Should We Rely on AI to Help Avoid Bias in Patient Selection for Major Surgery?
Sign Up to like & getrecommendations! Published in 2022 at "AMA journal of ethics"
DOI: 10.1001/amajethics.2022.773
Abstract: Many regard iatrogenic injuries as consequences of diagnosis or intervention actions. But inaction-not offering indicated major surgery-can also result in iatrogenic injury. This article explores some surgeons' overestimations of operative risk based on patients' race… read more here.
Keywords: major surgery; help avoid; surgery; rely help ... See more keywords
Perioperative Gabapentin Use and In-Hospital Adverse Clinical Events Among Older Adults After Major Surgery.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2022.3680
Abstract: Importance Gabapentin has been increasingly used as part of a multimodal analgesia regimen to reduce opioid use in perioperative pain management. However, the safety of perioperative gabapentin use among older patients remains uncertain. Objective To… read more here.
Keywords: gabapentin use; among older; major surgery; perioperative gabapentin ... See more keywords
Association Between the COVID-19 Pandemic and Insurance-Based Disparities in Mortality After Major Surgery Among US Adults
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.22360
Abstract: Key Points Question Was the COVID-19 pandemic associated with greater changes in mortality after major surgery among patients with Medicaid insurance or without insurance compared with patients with commercial insurance? Findings In this cross-sectional study… read more here.
Keywords: mortality major; insurance; covid pandemic; major surgery ... See more keywords
Population-Based Estimates of 1-Year Mortality After Major Surgery Among Community-Living Older US Adults.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA surgery"
DOI: 10.1001/jamasurg.2022.5155
Abstract: Importance Despite their importance to guiding public health decision-making and policies and to establishing programs aimed at improving surgical care, contemporary nationally representative mortality data for geriatric surgery are lacking. Objective To calculate population-based estimates… read more here.
Keywords: community living; mortality; year; major surgery ... See more keywords
Cardiovascular death and progression to end‐stage renal disease after major surgery in elderly patients
Sign Up to like & getrecommendations! Published in 2020 at "BJS Open"
DOI: 10.1002/bjs5.50232
Abstract: Reliable estimates for risk of cardiovascular‐specific mortality and progression to end‐stage renal disease (ESRD) among elderly patients undergoing major surgery are not available. This study aimed to develop simple risk scores to predict these events. read more here.
Keywords: renal disease; major surgery; stage renal; elderly patients ... See more keywords
Acute kidney disease beyond day 7 after major surgery: a secondary analysis of the EPIS-AKI trial
Sign Up to like & getrecommendations! Published in 2024 at "Intensive Care Medicine"
DOI: 10.1007/s00134-023-07314-2
Abstract: Acute kidney disease (AKD) is a significant health care burden worldwide. However, little is known about this complication after major surgery. We conducted an international prospective, observational, multi-center study among patients undergoing major surgery. The… read more here.
Keywords: postoperative aki; major surgery; early postoperative; aki ... See more keywords
Intravenous maintenance fluid tonicity and hyponatremia after major surgery- a cohort study.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of surgery"
DOI: 10.1016/j.ijsu.2019.04.019
Abstract: BACKGROUND Intravenous maintenance fluid (IMF) tonicity and composition influence plasma electrolyte balance. OBJECTIVE To determine if hypotonic IMF therapy contributes to post-surgical hyponatremia. SETTING Single-center tertiary institution. PARTICIPANTS Adults who underwent major surgery and received… read more here.
Keywords: surgery; hyponatremia; major surgery; post surgical ... See more keywords
The effect of human albumin administration on postoperative renal function following major surgery: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-62495-0
Abstract: Optimal fluid management during major surgery is of considerable concern to anesthesiologists. Although crystalloids are the first choice for fluid management, the administration of large volumes of crystalloids is associated with poor postoperative outcomes. Albumin… read more here.
Keywords: major surgery; albumin administration; renal function; surgery ... See more keywords
Mitochondrial damage drives T-cell immunometabolic paralysis after major surgery
Sign Up to like & getrecommendations! Published in 2025 at "EMBO Molecular Medicine"
DOI: 10.1038/s44321-025-00324-1
Abstract: Cytotoxic T cell (CTL) dysfunction is a hallmark of immune paralysis after major surgery, increasing susceptibility to severe nosocomial infections and contributing to mortality in critically ill patients. The mechanisms remain poorly understood. We demonstrate… read more here.
Keywords: surgery; ctl; major surgery; function ... See more keywords
2506. Reactivation of Latent Cytomegalovirus Infection Following Major Surgery: Risk Factors and Outcomes
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.2158
Abstract: Abstract Background Reactivation of latent cytomegalovirus infection can occur in nonimmunocompromised individuals during critical illness and may be associated with increased morbidity and mortality. However, few studies have focused on patients undergoing major surgery. Our… read more here.
Keywords: surgery; major surgery; board member; risk factors ... See more keywords
Pre-operative withholding of infliximab and the risk of infections after major surgery in patients with rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2020 at "Rheumatology"
DOI: 10.1093/rheumatology/keaa291
Abstract: OBJECTIVES Withholding TNF inhibitors (TNFI) before surgery has been recommended due to concern for post-operative infection. We examined the risks of post-operative infections and mortality in patients with RA in relation to the pre-operative timing… read more here.
Keywords: risk; surgery; major surgery; pre operative ... See more keywords