Controlled Human Malaria Infection (CHMI) Studies: Over 100 Years of Experience with Parasite Injections.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9550-9_7
Abstract: Human experimentation by deliberate infection with malarial parasites seems unethical yet has a long history in infectious disease research. After rigorous screening, volunteers are inoculated with Plasmodium sporozoites or blood stages and monitored under strict… read more here.
Keywords: controlled human; infection; malaria infection; chmi studies ... See more keywords
Development of multi-epitope driven subunit vaccine in secretory and membrane protein of Plasmodium falciparum to convey protection against malaria infection.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.05.082
Abstract: Malaria infection is the severe health concern for a long time. As per the WHO reports, the malarial infection causes huge mortality all around the world and is incomparable with any other infectious diseases. The… read more here.
Keywords: subunit vaccine; malaria infection; vaccine; epitope ... See more keywords
Malaria infection and the risk of epilepsy: a meta-analysis
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DOI: 10.1017/s0031182022001780
Abstract: Abstract Abstract Epilepsy, a chronic disease of the central nervous system, is highly prevalent in malaria-endemic regions. Therefore, several studies have evaluated the associations between malaria infection and epilepsy development. A meta-analysis of observational studies… read more here.
Keywords: meta analysis; malaria infection; analysis; epilepsy ... See more keywords
Volatile biomarkers of symptomatic and asymptomatic malaria infection in humans
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1801512115
Abstract: Significance Malaria elimination efforts are hindered by the prevalence of asymptomatic infections, which frequently go undetected and untreated. Consequently, there is a pressing need for improved diagnostic screening methods. Based on extensive collections of skin… read more here.
Keywords: symptomatic asymptomatic; asymptomatic infections; volatile biomarkers; microscopy ... See more keywords
Towards functional antibody-based vaccines to prevent pre-erythrocytic malaria infection
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DOI: 10.1080/14760584.2017.1295853
Abstract: ABSTRACT Introduction: An effective malaria vaccine would be considered a milestone of modern medicine, yet has so far eluded research and development efforts. This can be attributed to the extreme complexity of the malaria parasites,… read more here.
Keywords: antibody based; infection; malaria infection; vaccine ... See more keywords
Asymptomatic Malaria Infection and Their Antibodies Against Malaria: A Study in Abra de Ilog, Occidental Mindoro, Philippines
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DOI: 10.1093/ajcp/aqz121.028
Abstract: Human malaria, caused by four species of Plasmodium, namely P falciparum, P vivax, P malariae, and P ovale, remains a health problem of global concern, with one to two million deaths annually and risking about… read more here.
Keywords: ilog occidental; abra ilog; occidental mindoro; malaria infection ... See more keywords
High burden of malaria among Malawian adults on antiretroviral therapy after discontinuing prophylaxis
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DOI: 10.1097/qad.0000000000003317
Abstract: Objective: Many individuals living with the human immunodeficiency virus (HIV) infection and receiving antiretroviral therapy (ART) reside in areas at high risk for malaria but how malaria affects clinical outcomes is not well described in… read more here.
Keywords: clinical malaria; malaria infection; antiretroviral therapy; infection ... See more keywords
Deliberately infecting healthy volunteers with malaria parasites: Perceptions and experiences of participants and other stakeholders in a Kenyanâbased malaria infection study
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DOI: 10.1111/bioe.12781
Abstract: Controlled human malaria infection (CHMI) studies involve the deliberate infection of healthy volunteers with malaria parasites under controlled conditions to study immune responses and/or test drug or vaccine efficacy. An empirical ethics study was embedded… read more here.
Keywords: research; volunteers malaria; infection; study ... See more keywords
EFFECT OF COMMUNITY-BASED SCHEDULED SCREENING AND TREATMENT (CSST) OF MALARIA IN PREGNANCY ON INFANT MALARIA INFECTION IN A SEASONAL MALARIA TRANSMISSION SETTING
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DOI: 10.1136/bmjgh-2016-000260.76
Abstract: Background Children born to mothers who had malaria in pregnancy have an increased risk of malaria infection in the first 24 months of life and they also experience earlier episodes of malaria compared to their… read more here.
Keywords: pregnancy; malaria; treatment; malaria pregnancy ... See more keywords
Geographical and temporal variation in reduction of malaria infection among children under 5 years of age throughout Nigeria
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DOI: 10.1136/bmjgh-2020-004250
Abstract: Introduction Global progress in reducing malaria has stalled since 2015. Analysis of the situation is particularly needed in Nigeria, the country with by far the largest share of the burden, where approximately a quarter of… read more here.
Keywords: variation; pradj; years age; prevalence ... See more keywords
MULTIPLE PERIODIC SOLUTIONS OF A WITHIN-HOST MALARIA INFECTION MODEL WITH TIME DELAY
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DOI: 10.1142/s0218339021500108
Abstract: In this paper, we study a within-host malaria infection model recently proposed by Schneider et al. in 2018. The stability and Hopf bifurcation analysis at the interior equilibrium are carried out, finding that the basic… read more here.
Keywords: time delay; within host; malaria infection; host malaria ... See more keywords