Preliminary Evaluation of Artemisinin–Cholesterol Conjugates as Potential Drugs for the Treatment of Intractable Forms of Malaria and Tuberculosis
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DOI: 10.1002/cmdc.201700579
Abstract: To evaluate the feasibility of developing drugs that may be active against both malaria and tuberculosis (TB) by using in part putative cholesterol transporters in the causative pathogens and through enhancement of passive diffusion in… read more here.
Keywords: artemisinin cholesterol; cholesterol; tuberculosis; malaria tuberculosis ... See more keywords
Insights into Integrated Lead Generation and Target Identification in Malaria and Tuberculosis Drug Discovery
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DOI: 10.1021/acs.accounts.6b00631
Abstract: Conspectus New, safe and effective drugs are urgently needed to treat and control malaria and tuberculosis, which affect millions of people annually. However, financial return on investment in the poor settings where these diseases are… read more here.
Keywords: drug; malaria tuberculosis; tuberculosis drug; drug discovery ... See more keywords
mRNA vaccines: a new opportunity for malaria, tuberculosis and HIV
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1172691
Abstract: The success of the first licensed mRNA-based vaccines against COVID-19 has created a widespread interest on mRNA technology for vaccinology. As expected, the number of mRNA vaccines in preclinical and clinical development increased exponentially since… read more here.
Keywords: mrna; malaria tuberculosis; tuberculosis hiv; mrna vaccines ... See more keywords