Articles with "malat1" as a keyword



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Long noncoding RNA MALAT1 promotes the stemness of esophageal squamous cell carcinoma by enhancing YAP transcriptional activity

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Published in 2019 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12676

Abstract: The tumor promoting roles of long noncoding RNA (lncRNA) MALAT1 have been revealed in various cancers; however, its roles in esophageal squamous cell carcinoma (ESCC) have not previously been disclosed. In this study, we found… read more here.

Keywords: long noncoding; noncoding rna; malat1; escc cells ... See more keywords
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Long non‐coding RNA MALAT1 sponges miR‐149 to promote inflammatory responses of LPS‐induced acute lung injury by targeting MyD88

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Published in 2019 at "Cell Biology International"

DOI: 10.1002/cbin.11235

Abstract: Acute lung injury (ALI) caused by sepsis occurs early and the condition is severe, and is also an important reason for accelerating the death of patients. Increasing evidence has identified long non‐coding RNA (lncRNA) metastasis… read more here.

Keywords: lung injury; lps induced; mir 149; malat1 ... See more keywords
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LncRNA MALAT1 promotes decidualization of endometrial stromal cells via sponging miR‐498‐3p and targeting histone deacetylase 4

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Published in 2022 at "Cell Biology International"

DOI: 10.1002/cbin.11814

Abstract: Decidualization of human endometrial stromal cells (hESCs) is important for the maintenance of a successful pregnancy. Histone deacetylase 4 (HDAC4) was reported to be involved in the dysfunction of decidua‐derived mesenchymal stem cells. However, the… read more here.

Keywords: mir 498; endometrial stromal; hescs; hdac4 ... See more keywords
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A non‐canonical tumor suppressive role for the long non‐coding RNA MALAT1 in colon and breast cancers

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Published in 2018 at "International Journal of Cancer"

DOI: 10.1002/ijc.31386

Abstract: Long noncoding RNAs (lncRNAs) constitute one of the largest classes of transcripts and have been widely implicated in various diseases such as cancer. Increasing evidence suggests that several lncRNAs are dysregulated and play critical roles… read more here.

Keywords: colon breast; malat1; breast cancers; non canonical ... See more keywords
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Long non‐coding RNA MALAT1 promotes oral squamous cell carcinoma development via microRNA‐125b/STAT3 axis

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Published in 2018 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.26185

Abstract: Oral squamous cell carcinoma (OSCC), as the most common type of oral cancer, is responsible for almost 3% of all malignant tumors worldwide. Non‐coding RNAs such as lncRNAs and microRNAs have been involved in many… read more here.

Keywords: mir 125b; oral squamous; malat1; cell ... See more keywords
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Long noncoding RNA MALAT1 mediates cardiac fibrosis in experimental postinfarct myocardium mice model

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.27117

Abstract: Cardiac fibrosis is a pathological remodeling response to myocardial infarction (MI) and impairs cardiac contractility. Long noncoding RNA (lncRNA) metastasis‐associated lung adenocarcinoma transcript 1 (MALAT1) is increased in patients with MI. However, the functions of… read more here.

Keywords: long noncoding; fibrosis; noncoding rna; cardiac fibrosis ... See more keywords
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The long non‐coding RNA MALAT1 promotes ovarian cancer progression by regulating RBFOX2‐mediated alternative splicing

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Published in 2019 at "Molecular Carcinogenesis"

DOI: 10.1002/mc.22919

Abstract: Ovarian cancer metastasizes via direct seeding, whereby cancer cells shed from the primary site, resist cell death in the peritoneal cavity, then metastasize to peritoneal organs. We sought to identify molecular mechanisms that facilitate ovarian… read more here.

Keywords: long non; malat1; rbfox2; expression ... See more keywords
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LncRNA MALAT1 modified progression of clear cell kidney carcinoma (KIRC) by regulation of miR‐194‐5p/ACVR2B signaling

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Published in 2019 at "Molecular Carcinogenesis"

DOI: 10.1002/mc.22926

Abstract: This investigation was purposed to extrapolate whether and how lncRNA MALAT1, miR‐194‐5p, and ACVR2B altered development of clear cell kidney carcinoma (KIRC). We totally gathered 318 pairs of KIRC tissues and adjacent normal tissues, and… read more here.

Keywords: malat1 mir; malat1; acvr2b; kirc ... See more keywords
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LncRNA MALAT1 Promotes Oxygen-Glucose Deprivation and Reoxygenation Induced Cardiomyocytes Injury Through Sponging miR-20b to Enhance beclin1-Mediated Autophagy

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Published in 2019 at "Cardiovascular Drugs and Therapy"

DOI: 10.1007/s10557-019-06902-z

Abstract: LncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is reported to be highly expressed in myocardial I/R injury and closely related to autophagy. However, the exact biological role of MALAT1 and its underlying mechanism in myocardial… read more here.

Keywords: beclin1; glucose deprivation; malat1; oxygen glucose ... See more keywords
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Long Non-coding RNA MALAT1 Upregulates ZEB2 Expression to Promote Malignant Progression of Glioma by Attenuating miR-124.

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Published in 2020 at "Molecular neurobiology"

DOI: 10.1007/s12035-020-02165-0

Abstract: Long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been shown to play a critical role in the development of several malignancies. However, the potential molecular mechanism of MALAT1 in glioma remains unclear.… read more here.

Keywords: glioma; long non; malat1; non coding ... See more keywords
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Downregulation of lncRNA MALAT1 contributes to renal functional improvement after duodenal-jejunal bypass in a diabetic rat model

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Published in 2018 at "Journal of Physiology and Biochemistry"

DOI: 10.1007/s13105-018-0636-y

Abstract: Ameliorated renal function has been reported after bariatric surgery, but the mechanisms underlying this phenomenon are not well-studied. To investigate whether the long non-coding RNA (lncRNA) MALAT1 mediates the amelioration of diabetic nephropathy after duodenal-jejunal… read more here.

Keywords: surgery; malat1; duodenal jejunal; lncrna malat1 ... See more keywords