Utilizing a Mini-Humidifier To Deposit Matrix for MALDI Imaging.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b01714
Abstract: MALDI mass spectrometry imaging (MALDI-MSI) is a powerful tool to study endogenous metabolites. The process of matrix deposition is crucial for a high-quality imaging result. Commercial instruments for matrix deposition are expensive. Low-cost methods like… read more here.
Keywords: deposit matrix; matrix; mini humidifier; maldi imaging ... See more keywords
Hydrogen/Deuterium exchange aids compounds identification for LC-MS and MALDI imaging lipidomics.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b02461
Abstract: We present the novel approach for the increasing reliability of the compound identification for LC-MS and MALDI imaging lipidomics. Our approach is based on the characterization of compounds not only by the elution time, accurate… read more here.
Keywords: identification maldi; maldi imaging; exchange; approach ... See more keywords
Advanced Methods for MALDI-MS Imaging of the Chemical Communication in Microbial Communities.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b03772
Abstract: Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) is increasingly used to visualize the chemical communication between microorganisms. However, to fully exploit the potential of this label-free technique, crucial methodological advances are still needed. In… read more here.
Keywords: chemical communication; methods maldi; maldi imaging; advanced methods ... See more keywords
Utilizing PET and MALDI Imaging for Discovery of a Targeted Probe for Brain Endocannabinoid α/β-Hydrolase Domain 6 (ABHD6).
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01485
Abstract: Multimodal imaging provides rich biological information, which can be exploited to study drug activity, disease associated phenotypes, and pharmacological responses. Here we show discovery and validation of a new probe targeting the endocannabinoid α/β-hydrolase domain… read more here.
Keywords: maldi imaging; endocannabinoid hydrolase; brain; domain abhd6 ... See more keywords
Self-assembling peptides imaged by correlated liquid cell transmission electron microscopy and MALDI-imaging mass spectrometry
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-12660-1
Abstract: We describe the observation of stimuli-induced peptide-based nanoscale assemblies by liquid cell transmission electron microscopy (LCTEM). LCTEM offers the opportunity to directly image nanoscale materials in liquid. Despite broad interest in characterizing biological phenomena, electron… read more here.
Keywords: mass spectrometry; microscopy; imaging mass; maldi imaging ... See more keywords
Fungus-Growing Ant's Microbial Interaction of Streptomyces sp. and Escovopsis sp. through Molecular Networking and MALDI Imaging
Sign Up to like & getrecommendations! Published in 2019 at "Natural Product Communications"
DOI: 10.1177/1934578x1901400117
Abstract: Microbes associated with fungus-growing ants represent a poorly explored source of natural products. In this study, we used mass spectrometry-based dereplication techniques for identifying a set of secondary metabolites produced during the microbial interaction between… read more here.
Keywords: interaction streptomyces; maldi imaging; microbial interaction; growing ant ... See more keywords
Prefabricated platinum nanomaterial matrix for MALDI-MS imaging of oligosaccharides and lipids in plant tissues
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2023.1105374
Abstract: Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) can visualize the spatial distribution characteristics of molecules in tissues in situ, in which the matrix plays a key role. In this paper, we propose a platinum… read more here.
Keywords: matrix; maldi imaging; platinum nanomaterial; matrix maldi ... See more keywords
Impact of Skin Tissue Collection Method on Downstream MALDI-Imaging
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12060497
Abstract: MALDI imaging is a novel technique with which to study the pathophysiologies of diseases. Advancements in the field of metabolomics and lipidomics have been instrumental in mapping the signaling pathways involved in various diseases, such… read more here.
Keywords: maldi imaging; ffpe fresh; fresh frozen; collection ... See more keywords
Mapping the Lipids of Skin Sebaceous Glands and Hair Follicles by High Spatial Resolution MALDI Imaging Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15040411
Abstract: Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a technology that utilizes the high sensitivity and specificity of mass spectrometry, combined with a high spatial resolution to characterize the molecular species present in skin… read more here.
Keywords: mass spectrometry; maldi imaging; maldi; imaging mass ... See more keywords