Applications of Matrix-Assisted Laser Desorption Ionization In-Source Decay Mass Spectrometry.
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DOI: 10.1007/978-3-030-15950-4_3
Abstract: Matrix-Assisted Laser Desorption Ionization In-Source Decay (MALDI-ISD) Mass Spectrometry is a very powerful tool for providing terminal sequence information of biomolecules with minimal sample preparations. Fragmentation is induced at the position where hydrogen radical transfers… read more here.
Keywords: ionization source; assisted laser; laser desorption; maldi isd ... See more keywords
Ultraviolet-Laser-Induced Electron Transfer from Peptides to an Oxidizing Matrix: Study of the First Step of MALDI In-Source Decay Mass Spectrometry.
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DOI: 10.1021/jasms.0c00186
Abstract: Although the N-H bond in peptide backbones is stronger than the C-H bond, hydrogen abstraction from the amide nitrogen is considered to be the initial step in the Cα-C bond cleavage of peptide backbones by… read more here.
Keywords: isd; bond; abstraction; oxidizing matrix ... See more keywords
Experimental and Theoretical Investigation of MALDI In-Source Decay of Peptides with a Reducing Matrix: What Is the Initial Fragmentation Step?
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DOI: 10.1021/jasms.2c00066
Abstract: Matrix-assisted laser desorption/ionization in-source decay (MALDI-ISD) with a reducing matrix is believed to be initiated by hydrogen transfer from the matrix to the peptide. Several new matrices have recently been developed to achieve more efficient… read more here.
Keywords: fragmentation; source decay; reducing matrix; maldi isd ... See more keywords