MALDI Profiling and Applications in Medicine.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-15950-4_2
Abstract: Matrix assisted laser desorption ionization (MALDI) mass spectrometry allows for the rapid profiling of different biomolecular species from both biofluids and tissues. Whilst originally focused upon the analysis of intact proteins and peptides, MALDI mass… read more here.
Keywords: medicine; profiling applications; maldi profiling; mass spectrometry ... See more keywords
Infrared MALDI mass spectrometry imaging of TLC-separated glycosphingolipids with emphasis on Shiga toxin receptors isolated from human colon epithelial cells
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Mass Spectrometry"
DOI: 10.1016/j.ijms.2016.11.008
Abstract: Abstract Thin-layer chromatography (TLC) combined with infrared MALDI mass spectrometry (IR-MALDI-MS) is a powerful analytical tool for detection and structural characterization of glyco- and phospholipids directly from the TLC plate. Here we coupled a pulsed… read more here.
Keywords: maldi mass; tlc; infrared maldi; mass spectrometry ... See more keywords
3D MALDI Mass Spectrometry Imaging of a Single Cell: Spatial Mapping of Lipids in the Embryonic Development of Zebrafish
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-14949-x
Abstract: The zebrafish (Danio rerio) has been widely used as a model vertebrate system to study lipid metabolism, the roles of lipids in diseases, and lipid dynamics in embryonic development. Here, we applied high-spatial resolution matrix-assisted… read more here.
Keywords: mass spectrometry; embryonic development; maldi mass; imaging single ... See more keywords
Hydrazide-based reactive matrices for the sensitive detection of aldehydes and ketones by MALDI mass spectrometry imaging.
Sign Up to like & getrecommendations! Published in 2024 at "Chemical communications"
DOI: 10.1039/d4cc02475c
Abstract: A one-step, on-tissue chemical derivatisation method for MALDI mass spectrometry imaging was found to improve the detectability of aldehydes and ketones by charge-tagging. The developed reactive matrices, containing a UV-chromophore, ionisable moiety and hydrazide group,… read more here.
Keywords: mass spectrometry; spectrometry imaging; reactive matrices; aldehydes ketones ... See more keywords
MALDI Mass Spectrometry Imaging—Prognostic Pathways and Metabolites for Renal Cell Carcinomas
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14071763
Abstract: Simple Summary Renal cell carcinoma (RCC) is the seventh most common cancer type and accounts for more than 80% of all renal tumors. Nevertheless, prognostic biomarkers for RCC are still missing. Therefore, we analyzed a… read more here.
Keywords: cell; renal cell; mass spectrometry; rcc ... See more keywords