Swimming training mitigates the sex-specific hepatic disruption caused by a high-calorie diet: The putative modulation of Nrf2/Keap-1 pathway in male mice.
Sign Up to like & getrecommendations! Published in 2021 at "Cell biochemistry and function"
DOI: 10.1002/cbf.3631
Abstract: This study investigated whether swimming protocol induces adaptations to sex-specific oxidative stress and Nrf2/Keap-1 pathway in the liver of mice fed a high-calorie diet (HCD) during the early life period. Male and female Swiss mice… read more here.
Keywords: sex specific; nrf2; male mice; high calorie ... See more keywords
A novel mouse model overexpressing Nocturnin results in decreased fat mass in male mice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28623
Abstract: Nocturnin (NOCT) belongs to the Mg2+ dependent Exonucleases, Endonucleases, Phosphatase (EEP) family of enzymes that exhibit various functions in vitro and in vivo. NOCT is known to function as a deadenylase, cleaving poly‐A tails from… read more here.
Keywords: male mice; novel mouse; fat mass;
Greater neurodegeneration and behavioral deficits after single closed head traumatic brain injury in adolescent versus adult male mice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24535
Abstract: Traumatic brain injury (TBI) is a major public health concern affecting 2.8 million people per year in the United States, of whom about 1 million are children under 19 years old. Animal models of TBI… read more here.
Keywords: traumatic brain; closed head; male mice; mice ... See more keywords
Interleukin‐18 mediated inflammatory brain injury after intracerebral hemorrhage in male mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25044
Abstract: Interleukin‐18 (IL‐18), a pro‐inflammatory cytokine, is thought to be associated with inflammation in many neurological diseases such as ischemic stroke and poststroke depression, but the role of IL‐18 in inflammatory injury after intracerebral hemorrhage (ICH)… read more here.
Keywords: brain; injury intracerebral; brain injury; injury ... See more keywords
Effect of inorganic mercury exposure on reproductive system of male mice: Immunosuppression and fibrosis in testis.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental toxicology"
DOI: 10.1002/tox.23378
Abstract: Mercury as a toxic heavy metal will accumulate in the body and induce various diseases through the food chain. However, it is unknown that the detailed mechanism of reproductive disorder induced by inorganic mercury in… read more here.
Keywords: immunosuppression fibrosis; mercury; exposure; male mice ... See more keywords
Chemokine-like receptor 1 deficiency leads to lower bone mass in male mice
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-018-2944-3
Abstract: The adipokine Chemerin and its receptor, chemokine-like receptor 1 (CMKLR1), are associated with osteoblastogenic differentiation of mesenchymal stem cells (MSCs) and osteoclastogenic differentiation of osteoclast precursors in vitro, suggesting that CMKLR1 would affect the bone… read more here.
Keywords: cmklr1; male mice; bone; bone mass ... See more keywords
Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice
Sign Up to like & getrecommendations! Published in 2019 at "GeroScience"
DOI: 10.1007/s11357-019-00065-3
Abstract: Disruptions in growth hormone/insulin-like growth factor-1 (GH/IGF-1) signaling have been linked to improved longevity in mice and humans. Nevertheless, while IGF-1 levels are associated with increased cancer risk, they have been paradoxically implicated with protection… read more here.
Keywords: central igf; male mice; igf; brain igf ... See more keywords
Potential Protective Effect of Riboflavin Against Pathological Changes in the Main Organs of Male Mice Induced by Fluoride Exposure.
Sign Up to like & getrecommendations! Published in 2021 at "Biological trace element research"
DOI: 10.1007/s12011-021-02746-7
Abstract: Long-term exposure to excessive fluorine could cause damage to various tissues and organs in human and animals. However, there is no effective antidote to prevent and cure fluorosis except for avoiding fluoride intake. As an… read more here.
Keywords: pathological changes; cerebral cortex; exposure; male mice ... See more keywords
Social experiences during adolescence affect anxiety-like behavior but not aggressiveness in male mice
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.03.017
Abstract: HighlightsEffects of adolescent social experiences were studied in male mice.Escapable adversity during this life phase affected anxiety‐like behavior.Escapable adversity however, did not alter aggressive behavior.Thus, anxiety and aggression were shaped differentially during adolescence. Abstract Adolescence… read more here.
Keywords: male mice; social experiences; like behavior; anxiety like ... See more keywords
Irs2 deficiency alters hippocampus-associated behaviors during young adulthood.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.04.101
Abstract: Type 2 diabetes mellitus (T2DM), characterized by hyperglycemia and insulin resistance, has been recognized as a risk factor for cognitive impairment and dementia, including Alzheimer's disease (AD). Insulin receptor substrate2 (IRS2) is a major component… read more here.
Keywords: insulin; hippocampus associated; irs2 deficiency; young adult ... See more keywords
Subchronic and mild social defeat stress downregulates peripheral expression of sweet and umami taste receptors in male mice.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.09.063
Abstract: Depression is associated with taste disorders; however, the mechanisms by which mental stress affects taste perception are not well understood. This study aimed to elucidate the effects of psychosocial stress on peripheral taste-sensing systems using… read more here.
Keywords: taste; sweet umami; male mice; stress ... See more keywords