Maternal nicotine intoxication before pregnancy induces depressive- and anxiety-like behaviors as well as cognitive deficits in male offspring and correlates with neurobiological changes.
Sign Up to like & getrecommendations! Published in 2023 at "Brain and behavior"
DOI: 10.1002/brb3.3052
Abstract: INTRODUCTION Maternal nicotine use has been suggested to affect the behavior of children and is linked to changes in neurological systems; however, the specific mechanism is yet to be understood. METHODS Mice were used to… read more here.
Keywords: anxiety like; male offspring; nicotine intoxication; maternal nicotine ... See more keywords
Nutritional Programming of Bone Structure in Male Offspring by Maternal Consumption of Citrus Flavanones
Sign Up to like & getrecommendations! Published in 2017 at "Calcified Tissue International"
DOI: 10.1007/s00223-017-0366-0
Abstract: Maternal exposure to hesperidin (HSP) and naringin (NAR) during pregnancy and lactation transiently compromised bone mineral density (BMD) and bone structure at the proximal tibia in female CD-1 offspring. We examined whether maternal consumption of HSP + NAR… read more here.
Keywords: age; hsp nar; bone; male offspring ... See more keywords
Maternal Roux-en-Y gastric bypass impairs insulin action and endocrine pancreatic function in male F1 offspring
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Nutrition"
DOI: 10.1007/s00394-019-01968-9
Abstract: Purpose Obesity is predominant in women of reproductive age. Roux-en-Y gastric bypass (RYGB) is the most common bariatric procedure that is performed in obese women for weight loss and metabolic improvement. However, some studies suggest… read more here.
Keywords: gastric bypass; roux gastric; male; male offspring ... See more keywords
Prenatal exposure to valproic acid is associated with altered neurocognitive function and neurogenesis in the dentate gyrus of male offspring rats
Sign Up to like & getrecommendations! Published in 2019 at "Brain Research"
DOI: 10.1016/j.brainres.2019.146403
Abstract: In pregnant women with epilepsy, it is imperative to balance the safety of the mother and the potential teratogenicity of anticonvulsants, which could cause impairments such as intellectual disability and cleft lip. In this study,… read more here.
Keywords: neurogenesis; dentate gyrus; valproic acid; offspring rats ... See more keywords
Gestational and lactational exposure to di-isobutyl phthalate via diet in maternal mice decreases testosterone levels in male offspring.
Sign Up to like & getrecommendations! Published in 2017 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2017.01.011
Abstract: Phthalates are a large family of ubiquitous environmental chemicals suspected of being endocrine disruptors, with exposure to these chemicals during prenatal and postnatal development possibly resulting in reproductive disorders. Di-isobutyl phthalate (DiBP) is widely used… read more here.
Keywords: isobutyl phthalate; exposure; testosterone; male offspring ... See more keywords
Effects of maternal exposure to PFOA on testes of male offspring mice.
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2021.129585
Abstract: This study was conducted to explore the effects of maternal exposure to perfluorooctanoic acid (PFOA) on testicular development of male offspring mice. 20 pregnant Kunming mice were randomly divided into control group and PFOA exposure… read more here.
Keywords: pfoa; offspring mice; exposure; effects maternal ... See more keywords
PCB52 exposure alters the neurotransmission ligand-receptors in male offspring and contributes to sex-specific neurodevelopmental toxicity.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental pollution"
DOI: 10.1016/j.envpol.2020.114715
Abstract: Polychlorinated biphenyls (PCBs) in the air are predominantly the less chlorinated congeners. Non-dioxin-like (NDL) low-chlorinated PCBs are more neurotoxic, and cause neurodevelopmental and neurobehavioral alterations in humans. However, the underlying mechanisms for this neurodevelopmental toxicity… read more here.
Keywords: neurodevelopmental toxicity; sex; male offspring; ligand receptors ... See more keywords
Early-life perfluorooctanoic acid exposure induces obesity in male offspring and the intervention role of chlorogenic acid.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental pollution"
DOI: 10.1016/j.envpol.2020.115974
Abstract: Perfluorooctanoic acid (PFOA) is an emerging organic pollutant (EOP) hazardous to human health. Effects of maternal PFOA exposure on offspring as well as the underlying mechanisms remain unclear. In this study, ICR mouse models of… read more here.
Keywords: perfluorooctanoic acid; pfoa exposure; exposure; male offspring ... See more keywords
Decreased H3K9ac level of KLF4 mediates podocyte developmental toxicity induced by prenatal caffeine exposure in male offspring rats.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2019.07.011
Abstract: This study aimed to verify the toxic effects of prenatal caffeine exposure (PCE) on the podocyte development in male offspring, and to explore the underlying intrauterine programming mechanisms. The pregnant rats were administered with caffeine… read more here.
Keywords: klf4; h3k9ac level; expression; male offspring ... See more keywords
(-)-Epicatechin reduces adiposity in male offspring of obese rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174419000345
Abstract: Abstract Objective: To determine whether (-)-epicatechin (Epi) could decrease visceral adipose tissue and improve the metabolic profile of male offspring rats, after maternal obesity was induced by a high-fat diet (HFD). Design: Maternal obesity in… read more here.
Keywords: offspring obese; epicatechin reduces; male; maternal obesity ... See more keywords
Dipeptidyl peptidase IV inhibition delays developmental programming of obesity and metabolic disease in male offspring of obese mothers
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174422000010
Abstract: Abstract Maternal obesity programs the offspring to metabolic diseases later in life; however, the mechanisms of programming are yet unclear, and no strategies exist for addressing its detrimental transgenerational effects. Obesity has been linked to… read more here.
Keywords: male offspring; maternal obesity; dppiv; obese mothers ... See more keywords