Articles with "male rat" as a keyword



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Resveratrol inhibits the activity of acid‐sensing ion channels in male rat dorsal root ganglion neurons

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Published in 2022 at "Journal of Neuroscience Research"

DOI: 10.1002/jnr.25060

Abstract: Resveratrol can relieve pain under various pain conditions. One of the mechanisms of resveratrol analgesia is the regulation of ion channels. Acid‐sensing ion channels (ASICs) are expressed predominantly in nociceptive sensory neurons to detect changes… read more here.

Keywords: acid sensing; resveratrol; male rat; sensing ion ... See more keywords
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The effect of doxazosin and sildenafil citrate combination on bladder tissue contractility, alpha adrenergic receptor, and iNOS subtype expression in a male rat model of partially bladder outlet obstruction

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Published in 2017 at "Neurourology and Urodynamics"

DOI: 10.1002/nau.23155

Abstract: Our aim was to investigate the effects of doxazosin, sildenafil, and their combination on bladder tissue contractility and adrenergic receptor (AR) and inducible nitric oxide synthase (iNOS) expression utilizing a male rat model of partial… read more here.

Keywords: combination bladder; male rat; tissue contractility; doxazosin sildenafil ... See more keywords
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Fos expression is increased in oxytocin neurons of female rats with a sexually conditioned mate preference for an individual male rat

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Published in 2020 at "Hormones and Behavior"

DOI: 10.1016/j.yhbeh.2019.104612

Abstract: Evidence suggests an important role of Pavlovian learning in sexual partner selection. Female rats that experience paced copulation with a male scented with a neutral odor selectively solicit and receive ejaculations from the scented male… read more here.

Keywords: preference; male rat; fos expression; oxytocin neurons ... See more keywords
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Maternal undernutrition programs the apelinergic system of adipose tissue in adult male rat offspring

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Published in 2017 at "Journal of Developmental Origins of Health and Disease"

DOI: 10.1017/s2040174416000702

Abstract: Based on the Developmental Origin of Health and Disease concept, maternal undernutrition has been shown to sensitize adult offspring to metabolic pathologies such as obesity. Using a model of maternal 70% food restriction in pregnant… read more here.

Keywords: adult; male rat; maternal undernutrition; rat offspring ... See more keywords
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Mixed “Antiandrogenic” Chemicals at Low Individual Doses Produce Reproductive Tract Malformations in the Male Rat

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Published in 2018 at "Toxicological Sciences"

DOI: 10.1093/toxsci/kfy069

Abstract: Biomonitoring efforts have clearly shown that all humans are exposed to chemical mixtures. Of concern is whether or not exposure to mixtures during pregnancy contributes to congenital abnormalities in children even when each chemical is… read more here.

Keywords: dose; reproductive tract; adverse effect; male rat ... See more keywords
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Transplantation of the Uterus in the Male Rat.

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Published in 2023 at "Transplantation"

DOI: 10.1097/tp.0000000000004599

Abstract: BACKGROUND Uterus transplantation (UTx) is one of the potential methods to cure absolute uterine factor infertility of transgender. However, this mostly comes with many technological challenges. METHODS Left inguinal UTx was performed in 13 castrated… read more here.

Keywords: transplantation uterus; uterus male; transsexual utx; transplantation ... See more keywords
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The protective effects of grape seed oil on induced osteoarthritis of the knee in male rat models

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Published in 2020 at "Journal of Orthopaedic Surgery and Research"

DOI: 10.1186/s13018-020-01932-y

Abstract: Background Osteoarthritis (OA), though being treated via various methods and medicines, is still a major healthcare concern mostly due to the increase in diagnosis of these age-related diseases. The present study aimed at investigating the… read more here.

Keywords: seed; male rat; grape seed; rat models ... See more keywords
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Proteomics-Based Retinal Target Engagement Analysis and Retina-Targeted Delivery of 17β-Estradiol by the DHED Prodrug for Ocular Neurotherapy in Males

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Published in 2021 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics13091392

Abstract: We examined the impact of 17β-estradiol (E2) eye drops on the modulation of the proteome profile in the male rat retina. With discovery-driven proteomics, we have identified proteins that were regulated by our treatment. These… read more here.

Keywords: male rat; estradiol; treatment; target engagement ... See more keywords
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Male rat leukocyte population dynamics predict a window for intervention in aging

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Published in 2022 at "eLife"

DOI: 10.7554/elife.76808

Abstract: Many age-associated changes in the human hematopoietic system have been reproduced in murine models; however, such changes have not been as robustly explored in rats despite the fact these larger rodents are more physiologically similar… read more here.

Keywords: age; leukocyte population; male rat; blood ... See more keywords