Physiologically based pharmacokinetic model for ethyl tertiary‐butyl ether and tertiary‐butyl alcohol in rats: Contribution of binding to α2u–globulin in male rats and high‐exposure nonlinear kinetics to toxicity and cancer outcomes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3412
Abstract: In cancer bioassays, inhalation, but not drinking water exposure to ethyl tertiary‐butyl ether (ETBE), caused liver tumors in male rats, while tertiary‐butyl alcohol (TBA), an ETBE metabolite, caused kidney tumors in male rats following exposure… read more here.
Keywords: tertiary butyl; male rats; exposure; etbe tba ... See more keywords
Protective effect of grape seed extract against chronic physical stress‐induced zona fasciculata injury in male rats: Functional, immunohistochemical and electron microscopic study
Sign Up to like & getrecommendations! Published in 2022 at "Microscopy Research and Technique"
DOI: 10.1002/jemt.24130
Abstract: In the present study, we investigated the antioxidant effect of grape seed extract (GSE) against chronic immobilization stress‐induced zona fasciculata injury in Wistar male rats. Thirty male rats were divided into three groups: Non‐stress group:… read more here.
Keywords: stress; zona fasciculata; stress induced; male rats ... See more keywords
ZL006 promotes migration and differentiation of transplanted neural stem cells in male rats after stroke
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24068
Abstract: New strategies must be developed to resolve the problems of stroke treatment. In recent years, stem cell–based therapy after stroke has come into the public and academic lens. Previously we have shown that uncoupling neuronal… read more here.
Keywords: male rats; differentiation; zl006; stem cells ... See more keywords
Prenatal undernutrition disrupted the sexual maturation, but not the sexual behavior, in male rats
Sign Up to like & getrecommendations! Published in 2017 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12045
Abstract: Exposure to various stressors, including psychological, metabolic, and immune, in the perinatal period induces long‐lasting effects in physiological function and increase the risk of metabolic disorders in later life. In the present study, sexual maturation… read more here.
Keywords: maturation sexual; sexual behavior; male rats; sexual maturation ... See more keywords
Modulatory effects of Saussurea lappa root aqueous extract against ethephon‐induced kidney toxicity in male rats
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22828
Abstract: Ethephon (2‐chloroethyl phosphonic acid) is a plant growth promoter used to control the plant growth process by liberating ethylene and stimulating the production of endogenous ethylene. Medicinal plants are sources of novel drug discovery targets.… read more here.
Keywords: male rats; root; saussurea lappa; ethephon ... See more keywords
Long‐term reproductive effects in male rats prenatally exposed to sodium arsenite
Sign Up to like & getrecommendations! Published in 2023 at "Environmental Toxicology"
DOI: 10.1002/tox.23756
Abstract: Arsenic is an environmental toxicant known to be a carcinogen and endocrine disruptor. Maternal exposure to arsenic has been associated with fetus malformation and reproductive disorders in male offspring. However, it is unclear the extent… read more here.
Keywords: long term; exposure; adult; exposed sodium ... See more keywords
Comparison of some behavioral effects of d- and l-methamphetamine in adult male rats
Sign Up to like & getrecommendations! Published in 2017 at "Psychopharmacology"
DOI: 10.1007/s00213-017-4623-8
Abstract: RationaleBoth l- and d-methamphetamine (l- and d-MA) are more potent to release norpepinephrine (NE) than dopamine, and the selectivity is greater for l-MA than d-MA. Little is known of the in vivo pharmacology of l-MA.ObjectiveThis… read more here.
Keywords: effects methamphetamine; behavioral effects; male rats; methamphetamine adult ... See more keywords
Nucleus accumbens dopamine increases sexual motivation in sexually satiated male rats
Sign Up to like & getrecommendations! Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-5142-y
Abstract: RationaleThe influence of the main dopaminergic brain regions controlling copulation, the medial preoptic area (mPOA) and the nucleus accumbens (NAcc), on male rat sexual behavior expression has not been fully established.ObjectiveThis work analyzes the sexual… read more here.
Keywords: receptor; male rats; sexually satiated; sexual motivation ... See more keywords
The psychoactive aminoalkylbenzofuran derivatives, 5-APB and 6-APB, mimic the effects of 3,4-methylenedioxyamphetamine (MDA) on monoamine transmission in male rats.
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05648-z
Abstract: RATIONALE The nonmedical use of new psychoactive substances (NPS) is a worldwide public health concern. The so-called "benzofury" compounds, 5-(2-aminopropyl)benzofuran (5-APB) and 6-(2-aminopropyl)benzofuran (6-APB), are NPS with stimulant-like properties in human users. These substances are… read more here.
Keywords: male rats; apb apb; monoamine; monoamine transmission ... See more keywords
Administration of vitamin D and aerobic training: recovery of lung apoptosis markers in male rats exposed to hydrogen peroxide
Sign Up to like & getrecommendations! Published in 2019 at "Sport Sciences for Health"
DOI: 10.1007/s11332-019-00546-0
Abstract: BackgroundApoptosis is one of the indications of programmed cell death (PCD) and is known as a physiological event in multicellular organisms. This study was designed to determine the effect of aerobic training alongside vitamin D… read more here.
Keywords: male rats; apoptosis; training; aerobic training ... See more keywords
Ethanolic extract of fenugreek seeds moderates dimethoate-induced pancreatic damage in male rats
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DOI: 10.1007/s11356-017-0749-9
Abstract: Dimethoate is a widely used organophosphate insecticide known to be toxic to the pancreas. The aim of this study is to detect the possible protective effects of the fenugreek seed ethanolic extract on the biochemical,… read more here.
Keywords: seed; male rats; group; ethanolic extract ... See more keywords