Extending the shikimate pathway for microbial production of maleate from glycerol in engineered Escherichia coli
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27700
Abstract: Maleate is one of the most important unsaturated four‐carbon dicarboxylic acids. It serves as an attractive building block in cosmetic, polymer, and pharmaceutical industries. Currently, industrial production of maleate relies mainly on chemical synthesis using… read more here.
Keywords: engineered escherichia; production; escherichia coli; maleate ... See more keywords
Evaluation of the effect of new formulation, food, or a proton pump inhibitor on the relative bioavailability of the smoothened inhibitor glasdegib (PF-04449913) in healthy volunteers
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-017-3472-9
Abstract: PurposeThis phase I open-label study investigated the oral bioavailability of two novel maleate salt-based glasdegib (PF-04449913) tablet formulations (small- and large-particle size) relative to the current clinical formulation (diHCl salt-based). In addition, the effect of… read more here.
Keywords: inhibitor; maleate; formulation; large particle ... See more keywords
Coordination Polymer Based on Nickel(II) Maleate and 4′-Phenyl-2,2′:6′,2″-Terpyridine: Synthesis, Crystal Structure and Conjugated Thermolysis
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DOI: 10.1007/s10904-019-01227-8
Abstract: New complex (1) based on nickel(II) maleate and 4′-phenyl-2,2′:6′,2″-terpyridine (L) was synthesized. The complex 1 is a 1D coordination polymer formed from a L-Ni(II) node bridged by maleate ligands and crystallizes in monoclinic form with… read more here.
Keywords: maleate; polymer; based nickel; maleate phenyl ... See more keywords
Synthesis and Characterization of Allyl Terpene Maleate Monomer
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DOI: 10.1038/s41598-019-55356-8
Abstract: Terpenes and their derivatives are sustainable, renewable chemicals that can be used as a complementary hydrocarbon. The exceptions are fossil-based feedstocks and lignin-based feedstocks. A simple method has been found to prepare allyl terpene maleate… read more here.
Keywords: terpene maleate; maleate; maleate monomer; monomer ... See more keywords
Tegaserod Maleate Suppresses the Growth of Gastric Cancer In Vivo and In Vitro by Targeting MEK1/2
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DOI: 10.3390/cancers14153592
Abstract: Gastric cancer (GC), ranking fifth in global incidence and fourth in mortality. The current treatments for GC include surgery, chemotherapy, and radiotherapy. Although management and treatment strategies for GC have been improved over the last… read more here.
Keywords: maleate; gastric cancer; targeting mek1; tegaserod maleate ... See more keywords
Anaphylaxis to Chlorpheniramine Maleate and Literature Review
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DOI: 10.5021/ad.2019.31.4.438
Abstract: Chlorpheniramine maleate is commonly used antihistamine. Since antihistamines are the main therapeutic agents for symptomatic treatment of urticaria, anaphylaxis to antihistamines may lead to errors in diagnosis and treatment. We report a case of anaphylaxis… read more here.
Keywords: anaphylaxis chlorpheniramine; chlorpheniramine maleate; intradermal test; maleate ... See more keywords