Articles with "maleimidation quinoxaline" as a keyword



Mn(I)-Catalyzed Preferential Electrophilic C3-Maleimidation in Quinoxaline Leading to Spirocyclization and Dehydrogenation of Succinimides.

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Published in 2023 at "Organic letters"

DOI: 10.1021/acs.orglett.3c01350

Abstract: A Mn(I)-catalyzed site-selective nondirected C3-maleimidation of quinoxaline is established. Herein, the electrophilic C3-metalation precedes over the o-directed strategy to access diversely substituted quinoxaline-appended succinimides. The products undergo PIFA-promoted C(sp2)-C(sp3) spirocyclization via π-electrons drifting from aryls… read more here.

Keywords: catalyzed preferential; maleimidation quinoxaline; spirocyclization; quinoxaline ... See more keywords