Ferroptosis-Enhanced Immunotherapy with an Injectable Dextran-Chitosan Hydrogel for the Treatment of Malignant Ascites in Hepatocellular Carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300517
Abstract: Malignant ascites in advanced hepatocellular carcinoma (HCC) is a complex clinical problem that lacks effective treatments. Due to the insensitivity of advanced HCC cells to traditional chemotherapies, low drug accumulation, and limited drug residence time… read more here.
Keywords: hydrogel; ssz hydrogel; malignant ascites; treatment ... See more keywords
Malignant ascites-derived organoid (MADO) cultures for gastric cancer in vitro modelling and drug screening
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-019-03004-z
Abstract: Malignant ascites (MA) is a common manifestation in advanced gastric cancer with peritoneal carcinomatosis and usually indicates a poor prognosis. However, lack of in vitro models that can faithfully recapitulate the characteristics of tumour cells… read more here.
Keywords: malignant ascites; gastric cancer; drug screening; vitro ... See more keywords
Pancreatic Neuroendocrine Tumor Presenting with Chylous Ascites: Multidisciplinary Workup to Differentiate from Malignant Ascites
Sign Up to like & getrecommendations! Published in 2022 at "Journal of General Internal Medicine"
DOI: 10.1007/s11606-022-07463-y
Abstract: Neuroendocrine tumors (NET) are rare, indolent tumors originating most commonly in the small intestine, followed by pancreas and lung. Diagnosis and staging of these tumors can be notoriously difficult due to unpredictable tumor localization and… read more here.
Keywords: tumor; multidisciplinary workup; malignant ascites; pancreatic neuroendocrine ... See more keywords
Engineered Apoptosis-Bioinspired Nanoparticles Initiate Immune Cascade for Cancer Immunotherapy of Malignant Ascites.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c19769
Abstract: Malignant ascites (MA) is a common symptom of peritoneal metastasis in liver cancer. Cancer immunotherapy can modulate immune cells to induce antitumor immune efficiency. Reprogramming tumor immune microenvironment (TIME) is a momentous strategy to overcome… read more here.
Keywords: malignant ascites; cancer; immune cascade; cancer immunotherapy ... See more keywords
Therapeutic Procedures for Malignant Ascites in a Palliative Care Outpatient Clinic.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of palliative medicine"
DOI: 10.1089/jpm.2017.0616
Abstract: BACKGROUND The optimal treatment of malignant ascites (MA) and feasibility of the management with free drainage remain unclear. OBJECTIVE To study the success of drainage, complications, and survival after paracentesis or insertion of an indwelling… read more here.
Keywords: malignant ascites; care outpatient; palliative care; days iqr ... See more keywords
Novel pegylated interferon‐β as strong suppressor of the malignant ascites in a peritoneal metastasis model of human cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Science"
DOI: 10.1111/cas.13176
Abstract: Malignant ascites manifests as an end‐stage event during the progression of a number of cancers and lacks a generally accepted standard therapy. Interferon‐β (IFN‐β) has been used to treat several cancer indications; however, little is… read more here.
Keywords: malignant ascites; novel pegylated; ifn; interferon ... See more keywords
Pigs in a blanket: an unusual presentation of malignant ascites in prostatic adenocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Case Reports"
DOI: 10.1136/bcr-2019-230899
Abstract: Malignant ascites in prostatic acinar adenocarcinoma is very rare. We present an 84-year-old man with a rare malignant ascites due to prostatic adenocarcinoma demonstrating hepatoid differentiation by immunohistochemistry. The patient was diagnosed with the malignant… read more here.
Keywords: blanket unusual; pigs blanket; malignant ascites; prostatic adenocarcinoma ... See more keywords
Tunneled Peritoneal Catheter Placement in Palliation of Malignant Ascites: A Study with Two Different Types of Catheters
Sign Up to like & getrecommendations! Published in 2019 at "BioMed Research International"
DOI: 10.1155/2019/4132396
Abstract: Objective(s) Malignant ascites (MA) is abnormal accumulation of fluid in the peritoneal cavity and has negative effects on the quality of life. The purpose of this retrospective study is to explore feasibility, safety and efficacy… read more here.
Keywords: catheter; malignant ascites; peritoneal catheter; catheter placement ... See more keywords
Injectable Hyaluronic Acid Hydrogel for the Co-Delivery of Gemcitabine Nanoparticles and Cisplatin for Malignant Ascites Therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2020.3002
Abstract: Malignant ascites indicate the presence of malignant cells in the peritoneal cavity that lower patient survival and reduce quality of life. Current chemotherapy regimens suffer from the dilution of ascites and rapid metabolism limiting their… read more here.
Keywords: injectable hyaluronic; hydrogel; malignant ascites; acid hydrogel ... See more keywords
MS275 as Class I HDAC inhibitor displayed therapeutic potential on malignant ascites by iTRAQ-based quantitative proteomic analysis
Sign Up to like & getrecommendations! Published in 2022 at "BMC Gastroenterology"
DOI: 10.1186/s12876-022-02101-7
Abstract: Background Malignant ascites is a manifestation of end stage events in a variety of cancers and is associated with significant morbidity. Epigenetic modulators play a key role in cancer initiation and progression, among which histone… read more here.
Keywords: cancer; class; malignant ascites; hdac ... See more keywords
Activation of LXRɑ/β by cholesterol in malignant ascites promotes chemoresistance in ovarian cancer
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DOI: 10.1186/s12885-018-5152-5
Abstract: BackgroundThe purpose of this study was to investigate the role of malignant ascites tumor microenvironment in ovarian cancer progression and chemoresistance.MethodsA total of 45 patients with ovarian cancer and three benign ascites were collected at… read more here.
Keywords: chemoresistance; malignant ascites; cholesterol; ovarian cancer ... See more keywords