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   Articles with "malignant behaviors" as a keyword



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Vasohibin 2 promotes malignant behaviors of pancreatic cancer cells by inducing epithelial‐mesenchymal transition via Hedgehog signaling pathway

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recommendations! Published in 2018 at "Cancer Medicine"

DOI: 10.1002/cam4.1752

Abstract: Based on previous findings, we hypothesized that Vasohibin 2 (VASH2) protein may induce epithelial‐mesenchymal transition (EMT) of pancreatic cancer (PC) cells by promoting the malignant behaviors of these cells. The present study aimed to test… read more here.

Keywords: malignant behaviors; mesenchymal transition; pancreatic cancer; epithelial mesenchymal ... See more keywords

EphrinA3 is a key regulator of malignant behaviors and a potential prognostic factor in lung adenocarcinoma

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recommendations! Published in 2022 at "Cancer Medicine"

DOI: 10.1002/cam4.4987

Abstract: As a member of the Ephrin protein family that elicits short distance cell‐cell signaling, EphrinA3 has been shown to promote or inhibit tumorigenesis depending on tumor types, but its roles and the underlying mechanisms in… read more here.

Keywords: ephrina3 key; key regulator; lung adenocarcinoma; regulator malignant ... See more keywords

CircRNA SEPT9 contributes to malignant behaviors of glioma cells via miR-432-5p-mediated regulation of LASP1

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recommendations! Published in 2021 at "Brain Research"

DOI: 10.1016/j.brainres.2021.147501

Abstract: BACKGROUND Circular RNA (circRNA) septin 9 (circSEPT9; hsa_circ_0005320) has been reported to be abnormally up-regulated in glioma. However, the exact role and working mechanism of circSEPT9 in glioma progression are barely known. METHODS RNA and… read more here.

Keywords: malignant behaviors; circsept9; glioma cells; mir 432 ... See more keywords

Retracted: LINC00518 Promotes Cell Malignant Behaviors via Influencing EIF4A3-Mediated mRNA Stability of MITF in Melanoma

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recommendations! Published in 2024 at "BioMed Research International"

DOI: 10.1155/2024/9846817

Abstract: [This retracts the article DOI: 10.1155/2022/3546795.]. read more here.

Keywords: behaviors via; linc00518 promotes; retracted linc00518; cell malignant ... See more keywords

Methyltransferase like 13 promotes malignant behaviors of bladder cancer cells through targeting PI3K/ATK signaling pathway

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recommendations! Published in 2024 at "Open Life Sciences"

DOI: 10.1515/biol-2022-0981

Abstract: Abstract Bladder cancer (BC) is the tenth most common tumor worldwide, characterized by high incidence rates and mortality. This study aimed to explore the role of Methyltransferase like 13 (METTL13) in BC cells. J82 and… read more here.

Keywords: methyltransferase like; bladder cancer; malignant behaviors; signaling pathway ... See more keywords

MIR503HG Overexpression Inhibits the Malignant Behaviors of Osteosarcoma Cells by Sponging miR-103a-3p.

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recommendations! Published in 2023 at "Critical reviews in eukaryotic gene expression"

DOI: 10.1615/critreveukaryotgeneexpr.2022042373

Abstract: Osteosarcoma (OS) is the most representative primary bone tumour in children and teenagers. This study explored the regulatory effects of long noncoding RNA MIR503HG (MIR503HG) on the biological functions of OS cells, and further investigated… read more here.

Keywords: mir503hg; mir 103a; malignant behaviors; expression mir503hg ... See more keywords

WNK1 in Malignant Behaviors: A Potential Target for Cancer?

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recommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.935318

Abstract: Metastasis is the major cause of mortality in cancer patients. Analyses of mouse models and patient data have implicated the protein kinase WNK1 as one of a handful of genes uniquely linked to a subset… read more here.

Keywords: wnk1 malignant; malignant behaviors; behaviors potential; target cancer ... See more keywords
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Circular RNA AKT3 governs malignant behaviors of esophageal cancer cells by sponging miR-17-5p

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recommendations! Published in 2021 at "World Journal of Gastroenterology"

DOI: 10.3748/wjg.v27.i3.240

Abstract: BACKGROUND Recent studies have demonstrated that circular RNA AKT3 (circAKT3) plays a crucial role in regulating the malignant phenotypes of tumor cells. However, the potential effects of circAKT3 on esophageal cancer have not been investigated.… read more here.

Keywords: esophageal cancer; malignant behaviors; circakt3; mir ... See more keywords

Pyruvate kinase M2 plays pivotal role on promoting PD-L1 expression and malignant behaviors of hepatoma cells

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recommendations! Published in 2025 at "Archives of Medical Science"

DOI: 10.5114/aoms/208245

Abstract: Pyruvate kinase M2(PKM2) is a key rate-limiting enzyme that regulates glucose metabolic reprogramming(Warburg effect), but the correlation between PKM2 and PD-L1 or malignant behaviors in hepatocellular carcinoma(HCC) cells remains unknown. This study explored the role… read more here.

Keywords: expression; malignant behaviors; expression pkm2; hcc cells ... See more keywords

NEAT1/miR-101-dependent Up-regulation of DNA-PKcs Enhances Malignant Behaviors of Pancreatic Ductal Adenocarcinoma Cells

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recommendations! Published in 2021 at "Journal of Cancer"

DOI: 10.7150/jca.58824

Abstract: Background: Although we previously revealed that DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is overexpressed in pancreatic ductal adenocarcinoma (PDAC) and important for gemcitabine resistance, the role of DNA-PKcs in the progression and metastasis of PDAC… read more here.

Keywords: malignant behaviors; neat1 mir; dna; mir 101 ... See more keywords