Articles with "malignant cells" as a keyword



Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

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Published in 2025 at "Molecular Oncology"

DOI: 10.1002/1878-0261.70012

Abstract: Hepatocellular carcinoma (HCC), the sixth most prevalent cancer globally, is characterized by high recurrence rates and poor prognosis. Investigating the heterogeneity of relapsed HCC and identifying key therapeutic targets may facilitate the design of effective… read more here.

Keywords: malignant cells; hepatocellular carcinoma; relapsed hcc; recurrence ... See more keywords

Recycling the Interspecific Relations with Epithelial Cells: Bacteria and Cancer Metabolic Symbiosis.

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Published in 2020 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-030-34025-4_4

Abstract: Several aspects of the human physiology are controlled by the microbiota that plays a key role in health and disease. In fact, microbial dysbiosis is associated with numerous diseases, including several types of cancer such… read more here.

Keywords: malignant cells; metabolic symbiosis; recycling interspecific; cancer ... See more keywords

Numerical method to evaluate the survival rate of malignant cells considering the distribution of treatment temperature field for magnetic hyperthermia

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Published in 2019 at "Journal of Magnetism and Magnetic Materials"

DOI: 10.1016/j.jmmm.2019.165458

Abstract: Abstract Magnetic hyperthermia ablates malignant cells by heating a tumor region when magnetic nanoparticles (MNPs) are subjected to a high-frequency magnetic field. The treatment effect for magnetic hyperthermia can be evaluated by the mortality of… read more here.

Keywords: treatment temperature; treatment; malignant cells; temperature ... See more keywords
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Does the use of melatonin overcome drug resistance in cancer chemotherapy?

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Published in 2018 at "Life sciences"

DOI: 10.1016/j.lfs.2018.01.024

Abstract: Our knowledge regarding the implications of melatonin in the therapy of numerous medical conditions, including cancer is constantly expanding. Melatonin can variably affect cancer pathology via targeting several key aspects of any neoplastic condition, including… read more here.

Keywords: drug resistance; malignant cells; resistance; resistance cancer ... See more keywords

Malignant cells from pleural fluids in malignant mesothelioma patients reveal novel mutations.

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Published in 2018 at "Lung cancer"

DOI: 10.1016/j.lungcan.2018.03.009

Abstract: OBJECTIVES Malignant mesothelioma (MM) is an asbestos related tumour affecting cells of serosal cavities. More than 70% of MM patients develop pleural effusions which contain tumour cells, representing a readily accessible source of malignant cells… read more here.

Keywords: malignant cells; tumour cells; cells pleural; reveal novel ... See more keywords

Lactobacilli enhance reactive oxygen species-dependent apoptosis-inducing signaling

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Published in 2017 at "Redox Biology"

DOI: 10.1016/j.redox.2017.01.015

Abstract: H2O2-producing lactobacilli in the vaginal fluid have been suggested to play a potential tumor-preventive role in addition to the control of undesirable microorganisms. As the vaginal fluid also contains a significant concentration of peroxidase that… read more here.

Keywords: apoptosis inducing; lactobacilli enhance; malignant cells; apoptosis ... See more keywords

A novel Fer/FerT targeting compound selectively evokes metabolic stress and necrotic death in malignant cells

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Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-00832-w

Abstract: Disruption of the reprogrammed energy management system of malignant cells is a prioritized goal of targeted cancer therapy. Two regulators of this system are the Fer kinase, and its cancer cell specific variant, FerT, both… read more here.

Keywords: death; malignant cells; metabolic stress; fer fert ... See more keywords

Evaluating mogamulizumab in the treatment of primary cutaneous T-cell lymphoma.

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Published in 2025 at "Immunotherapy"

DOI: 10.1080/1750743x.2025.2520153

Abstract: Mogamulizumab is a humanized monoclonal antibody targeting CCR4, a chemokine receptor expressed on T-cells, including malignant cells found in cutaneous T-cell lymphoma (CTCL). CTCL represents a heterogeneous group of skin lymphomas, with Mycosis Fungoides (MF)… read more here.

Keywords: cutaneous cell; malignant cells; treatment; cell lymphoma ... See more keywords

RIPK1 inhibition in malignant cells potentiates immunotherapy and radiotherapy outcome

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Published in 2024 at "Oncoimmunology"

DOI: 10.1080/2162402x.2024.2425465

Abstract: ABSTRACT Apoptosis, necroptosis and pro-inflammatory NF-κB-dependent signaling are repressed by receptor-interacting serine/threonine-protein kinase 1 (RIPK1). A recent paper in Immunity describes a small molecule inducing the proteolytic degradation of RIPK1. In preclinical experiments, this RIPK1… read more here.

Keywords: inhibition malignant; malignant cells; potentiates immunotherapy; radiotherapy ... See more keywords

UTILITY OF AUTOMATED HEMATOLOGY ANALYZER IN THE DETECTION OF MALIGNANT CELLS IN SEROUS EFFUSIONS

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Published in 2024 at "American Journal of Clinical Pathology"

DOI: 10.1093/ajcp/aqae129.175

Abstract: Although microscopic examination is the gold standard for body fluid malignant cytology, it has a higher turnaround time and inter observed variability. Screening of serous effusions for malignant cells using haematology methods of automated analysis… read more here.

Keywords: detection malignant; malignant cells; hematology; serous effusions ... See more keywords

Deep learning neural network of adenocarcinoma detection in effusion cytology

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Published in 2025 at "American Journal of Clinical Pathology"

DOI: 10.1093/ajcp/aqaf067

Abstract: Abstract Objective Cytologic examination, which confirms the presence or absence of malignant cells, detects malignant cells from various organs, with adenocarcinoma as the most common histologic type. We developed a deep learning model to detect… read more here.

Keywords: deep learning; detection; malignant cells; effusion cytology ... See more keywords