Recycling the Interspecific Relations with Epithelial Cells: Bacteria and Cancer Metabolic Symbiosis.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-34025-4_4
Abstract: Several aspects of the human physiology are controlled by the microbiota that plays a key role in health and disease. In fact, microbial dysbiosis is associated with numerous diseases, including several types of cancer such… read more here.
Keywords: malignant cells; metabolic symbiosis; recycling interspecific; cancer ... See more keywords
Numerical method to evaluate the survival rate of malignant cells considering the distribution of treatment temperature field for magnetic hyperthermia
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Magnetism and Magnetic Materials"
DOI: 10.1016/j.jmmm.2019.165458
Abstract: Abstract Magnetic hyperthermia ablates malignant cells by heating a tumor region when magnetic nanoparticles (MNPs) are subjected to a high-frequency magnetic field. The treatment effect for magnetic hyperthermia can be evaluated by the mortality of… read more here.
Keywords: treatment temperature; treatment; malignant cells; temperature ... See more keywords
Does the use of melatonin overcome drug resistance in cancer chemotherapy?
Sign Up to like & getrecommendations! Published in 2018 at "Life sciences"
DOI: 10.1016/j.lfs.2018.01.024
Abstract: Our knowledge regarding the implications of melatonin in the therapy of numerous medical conditions, including cancer is constantly expanding. Melatonin can variably affect cancer pathology via targeting several key aspects of any neoplastic condition, including… read more here.
Keywords: drug resistance; malignant cells; resistance; resistance cancer ... See more keywords
Malignant cells from pleural fluids in malignant mesothelioma patients reveal novel mutations.
Sign Up to like & getrecommendations! Published in 2018 at "Lung cancer"
DOI: 10.1016/j.lungcan.2018.03.009
Abstract: OBJECTIVES Malignant mesothelioma (MM) is an asbestos related tumour affecting cells of serosal cavities. More than 70% of MM patients develop pleural effusions which contain tumour cells, representing a readily accessible source of malignant cells… read more here.
Keywords: malignant cells; tumour cells; cells pleural; reveal novel ... See more keywords
Lactobacilli enhance reactive oxygen species-dependent apoptosis-inducing signaling
Sign Up to like & getrecommendations! Published in 2017 at "Redox Biology"
DOI: 10.1016/j.redox.2017.01.015
Abstract: H2O2-producing lactobacilli in the vaginal fluid have been suggested to play a potential tumor-preventive role in addition to the control of undesirable microorganisms. As the vaginal fluid also contains a significant concentration of peroxidase that… read more here.
Keywords: apoptosis inducing; lactobacilli enhance; malignant cells; apoptosis ... See more keywords
A novel Fer/FerT targeting compound selectively evokes metabolic stress and necrotic death in malignant cells
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-00832-w
Abstract: Disruption of the reprogrammed energy management system of malignant cells is a prioritized goal of targeted cancer therapy. Two regulators of this system are the Fer kinase, and its cancer cell specific variant, FerT, both… read more here.
Keywords: death; malignant cells; metabolic stress; fer fert ... See more keywords
High-resolution simulations of chromatin folding at genomic rearrangements in malignant B cells provide mechanistic insights into proto-oncogene deregulation
Sign Up to like & getrecommendations! Published in 2022 at "Genome Research"
DOI: 10.1101/gr.276028.121
Abstract: Genomic rearrangements are known to result in proto-oncogene deregulation in many cancers, but the link to genome 3D structure remains poorly understood. Here we used the highly-predictive heteromorphic polymer (HiP-HoP) model to predict chromatin conformations… read more here.
Keywords: ccnd1; proto oncogene; genomic rearrangements; oncogene deregulation ... See more keywords
Extent of intraluminal exfoliated malignant cells during surgery for colon cancer: Differences in cell abundance ratio between laparoscopic and open surgery
Sign Up to like & getrecommendations! Published in 2019 at "Asian Journal of Endoscopic Surgery"
DOI: 10.1111/ases.12617
Abstract: Laparoscopic colectomy with intracorporeal anastomosis is a minimally invasive surgical procedure for patients with colon cancer. However, there are often concerns about the presence of intraluminal exfoliated malignant cells in the intracorporeal anastomosis. This study… read more here.
Keywords: surgery; malignant cells; colon cancer; intraluminal exfoliated ... See more keywords
Characterization of Immunogenicity of Malignant Cells with Stemness in Intrahepatic Cholangiocarcinoma by Single-Cell RNA Sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Stem Cells International"
DOI: 10.1155/2022/3558200
Abstract: Cancer stem cells (CSCs) are responsible for long-term maintenance of tumors and thought to play a role in treatment resistance. The interaction between stemness and immunogenicity of CSCs in the intrahepatic cholangiocarcinoma (iCCA) is largely… read more here.
Keywords: intrahepatic cholangiocarcinoma; stemness malignant; immunogenicity; stemness ... See more keywords
Nuclear Morphology and the Biology of Cancer Cells
Sign Up to like & getrecommendations! Published in 2020 at "Acta Cytologica"
DOI: 10.1159/000508780
Abstract: Background: For more than a century, diagnostic pathologists have used morphologic abnormalities of the nucleus as essential diagnostic features to distinguish benign from malignant cells. These features include nuclear enlargement and increased nuclear-to-cytoplasmic ratio, nuclear… read more here.
Keywords: malignant cells; nuclear envelope; biology; cancer cells ... See more keywords
Hyperprogression of cutaneous T cell lymphoma after anti–PD-1 treatment
Sign Up to like & getrecommendations! Published in 2023 at "JCI Insight"
DOI: 10.1172/jci.insight.164793
Abstract: BACKGROUND Immune checkpoint blockade is an emerging treatment for T cell non-Hodgkin’s lymphoma (T-NHL), but some patients with T-NHL have experienced hyperprogression with undetermined mechanisms upon anti–PD-1 therapy. METHODS Single-cell RNA-Seq, whole-genome sequencing, whole-exome sequencing,… read more here.
Keywords: cell; cell lymphoma; hyperprogression; treatment ... See more keywords