The Potential of Cellular- and Viral-Based Immunotherapies for Malignant Glioma–Dendritic Cell Vaccines, Adoptive Cell Transfer, and Oncolytic Viruses
Sign Up to like & getrecommendations! Published in 2017 at "Current Neurology and Neuroscience Reports"
DOI: 10.1007/s11910-017-0754-x
Abstract: Purpose of ReviewMalignant gliomas, including glioblastoma and anaplastic astrocytoma, are the most frequent primary brain tumors and present with many treatment challenges. In this review, we discuss the potential of cellular- and viral-based immunotherapies in… read more here.
Keywords: viral based; malignant glioma; cellular viral; cell vaccines ... See more keywords
5-Aminolevulinic acid fluorescence guided resection of malignant glioma: Hong Kong experience.
Sign Up to like & getrecommendations! Published in 2018 at "Asian journal of surgery"
DOI: 10.1016/j.asjsur.2017.06.004
Abstract: BACKGROUND 5-Aminolevulinic Acid (5-ALA) induced fluorescence is useful in guiding glioma resection. The extent of 5-ALA accumulation is beyond gadolinium contrast enhancement.1,2 Supratotal resection may be achieved, potentially granting patients with better survival. We present… read more here.
Keywords: glioma; malignant glioma; fluorescence; aminolevulinic acid ... See more keywords
Novel approach to temozolomide resistance in malignant glioma: connexin43‐directed therapeutics
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DOI: 10.1016/j.coph.2018.05.002
Abstract: HighlightsCx43 regulates invasiveness, proliferation, and resistance of malignant glioma.Cx43 provides a permissive niche for the invasion and channel‐mediated TMZ resistance.Targeting Cx43 with C‐terminal peptidomimetics can sensitize glioblastoma to TMZ.Mechanism of action for peptidomimetics may be… read more here.
Keywords: malignant glioma; resistance malignant; resistance; cx43 ... See more keywords
Characterization of plasma-derived protoporphyrin-IX-positive extracellular vesicles following 5-ALA use in patients with malignant glioma
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DOI: 10.1016/j.ebiom.2019.09.025
Abstract: Summary Background Malignant gliomas are rapidly progressive brain tumors with high mortality. Fluorescence guided surgery (FGS) with 5-aminolevulinic acid (5-ALA) provides fluorescent delineation of malignant tissue, which helps achieve maximum safe resection. 5-ALA-based fluorescence is… read more here.
Keywords: malignant glioma; ala; positive evs; ppix positive ... See more keywords
Visible light-induced cytotoxicity of Ru,Os–polyazine complexes towards rat malignant glioma
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DOI: 10.1016/j.ica.2016.05.044
Abstract: Abstract Transition metal complexes capable of visible light-triggered cytotoxicity are appealing potential candidates for photodynamic therapy (PDT) of cancer. Two monometallic polyazine complexes, [(Ph2phen)2Ru(dpp)]2+ (1) and [(Ph2phen)2Os(dpp)]2+ (2) (Ph2phen = 4,7-diphenyl-1,10-phenanthroline; dpp = 2,3-bis(2-pyridyl)pyrazine), were synthesized, characterized and studied… read more here.
Keywords: malignant glioma; polyazine complexes; visible light; cytotoxicity ... See more keywords
Pattern of disease progression following stereotactic radiosurgery in malignant glioma patients
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2020.04.047
Abstract: INTRODUCTION The clinical benefit of stereotactic radiosurgery (SRS) in the treatment of malignant glioma remains controversial. We analyzed failure patterns of malignant gliomas following SRS to identify the clinical implications of SRS against these malignancies.… read more here.
Keywords: malignant glioma; srs; failure patterns; disease progression ... See more keywords
“Simple Methods to Derive Primary Malignant Glioma Cell Lines and Assay of Cellular Damage for Preclinical Studies”
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DOI: 10.1080/07357907.2018.1430814
Abstract: ABSTRACT Primary malignant glioma cell lines are being used for initial screening of anticancer agents. We utilized a simple mechanical disaggregation method for deriving cell lines from tumor tissues; and a Coverslip Culture-Acridine Orange Staining… read more here.
Keywords: malignant glioma; cell lines; primary malignant; cell ... See more keywords
P10.15 Molecular Classification of Malignant Glioma
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DOI: 10.1093/neuonc/nox036.333
Abstract: Background: Malignant glioma are devastating tumors with poor prognosis. In recent years, the classification of glioma have evolved greatly due to exploration of several molecular tools in addition ... read more here.
Keywords: molecular classification; glioma; classification malignant; malignant glioma ... See more keywords
GENE-12. ANALYSIS OF FAILURE PATTERNS IN MALIGNANT GLIOMA: EXPLORING THE GENETIC LANDSCAPE OF PATTERN OF FAILURE
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DOI: 10.1093/neuonc/noz175.414
Abstract: Failure patterns in malignant gliomas have been described in previous literatures, however, studies were limited to analyze clinical features to account for predisposition to distinct failure patterns. Present study aimed to describe the landscape of… read more here.
Keywords: patterns malignant; recurrence; malignant glioma; landscape ... See more keywords
Top-down stepwise refinement identifies coding and noncoding RNA-associated epigenetic regulatory maps in malignant glioma.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cellular and molecular medicine"
DOI: 10.1111/jcmm.17244
Abstract: With the emergence of the molecular era and retreat of the histology epoch in malignant glioma, it is becoming increasingly necessary to research diagnostic/prognostic/therapeutic biomarkers and their related regulatory mechanisms. While accumulating studies have investigated… read more here.
Keywords: noncoding rna; rna associated; coding noncoding; malignant glioma ... See more keywords
Production and Evaluation of an Avian IgY Immunotoxin against CD133+ for Treatment of Carcinogenic Stem Cells in Malignant Glioma: IgY Immunotoxin for the Treatment of Glioblastoma
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DOI: 10.1155/2019/2563092
Abstract: Background Glioblastoma is the most common malignant tumor of Central Nervous System. Despite the research in therapeutics, the prognosis is dismal. Malignant glioma stem cells (MGSCs) are a major cause of treatment failure and increasing… read more here.
Keywords: malignant glioma; cd133; treatment; igy ... See more keywords