Evaluating the Effect of HDAC8 Inhibition in Malignant Peripheral Nerve Sheath Tumors.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6527-4_27
Abstract: Malignant peripheral nerve sheath tumor (MPNST) is a highly aggressive disease with a dismal prognosis. The disease can occur sporadically or in patients with inherited neurofibromatosis (NF-1). MPNST is typically resistant to therapeutic intervention. Hence,… read more here.
Keywords: malignant peripheral; inhibition; hdac8 inhibition; mpnst ... See more keywords
BL1391: an established cell line from a human malignant peripheral nerve sheath tumor with unique genomic features
Sign Up to like & getrecommendations! Published in 2020 at "Human Cell"
DOI: 10.1007/s13577-020-00418-7
Abstract: Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive tumors, accounting for around 5% of all soft tissue sarcomas. A better understanding of the pathogenesis of these tumors and the development of effective treatments are needed.… read more here.
Keywords: cell line; malignant peripheral; peripheral nerve; cell ... See more keywords
Establishment and characterization of NCC-MPNST6-C1: a novel patient-derived cell line of malignant peripheral nerve sheath tumors.
Sign Up to like & getrecommendations! Published in 2021 at "Human cell"
DOI: 10.1007/s13577-021-00643-8
Abstract: Malignant peripheral nerve sheath tumors (MPNSTs) are a rare subtype of mesenchymal tumors that arise from the sheath of peripheral nerves. MPNSTs exhibit strong metastatic potential, leading to poor clinical outcomes. The clinical utility of… read more here.
Keywords: malignant peripheral; cell; cell line; ncc mpnst6 ... See more keywords
Large para-testicular intra-scrotal malignant peripheral nerve sheath tumor managed with radical penectomy: A case report
Sign Up to like & getrecommendations! Published in 2021 at "Urology Case Reports"
DOI: 10.1016/j.eucr.2021.101695
Abstract: Neurofibromatosis 1 is a relatively rare genetic disease characterized by widespread neurofibromas originating from the peripheral nervous system. Most growths are benign, but some carry a risk of transformation to malignant peripheral nerve sheath tumors.… read more here.
Keywords: malignant peripheral; peripheral nerve; nerve sheath; case ... See more keywords
Malignant Peripheral Nerve Sheath Tumor Arising in Schwannomatosis with Multiple Lung Metastases.
Sign Up to like & getrecommendations! Published in 2018 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.08.087
Abstract: BACKGROUND Malignant peripheral nerve sheath tumor (MPNST) is a kind of rare neurogenic malignancy, which usually arises from nerve fibers in any tissue and organ that have nerve fiber distributions, especially the trunk and extremities,… read more here.
Keywords: schwannomatosis; malignant peripheral; nerve sheath; nerve ... See more keywords
Synchronous Development of Multicentric Malignant Peripheral Nerve Sheath Tumors: Institutional Review.
Sign Up to like & getrecommendations! Published in 2018 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.12.088
Abstract: BACKGROUND Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft tissue sarcomas, with approximately 50% occurring in patients diagnosed with neurofibromatosis type 1 (NF-1). NF-1 occurs in approximately 1/3000 individuals, and given that the lifetime… read more here.
Keywords: malignant peripheral; pathology; synchronous development; mpnst ... See more keywords
The largest malignant peripheral nerve sheath arising from the gluteal region: case report.
Sign Up to like & getrecommendations! Published in 2019 at "British journal of neurosurgery"
DOI: 10.1080/02688697.2018.1562033
Abstract: We report a unique case of a huge malignant peripheral nerve sheath tumor with probable smooth muscle differentiation. read more here.
Keywords: malignant peripheral; nerve sheath; case; report ... See more keywords
Malignant peripheral nerve sheath tumor in children: A single-institute retrospective analysis
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Hematology and Oncology"
DOI: 10.1080/08880018.2017.1408730
Abstract: ABSTRACT Malignant peripheral nerve sheath tumors are rare tumors that originate from Schwann cells. Patients with neurofibromatosis type 1 are prone to develop these tumors. Due to their rarity and lack of established treatment, the… read more here.
Keywords: malignant peripheral; nerve sheath; sheath tumors; nerve ... See more keywords
Role of Histone H3K27 Trimethylation Loss as a Marker for Malignant Peripheral Nerve Sheath Tumor in Fine-Needle Aspiration and Small Biopsy Specimens
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqx060
Abstract: Objectives Accurate diagnosis of malignant peripheral nerve sheath tumor (MPNST) is often challenging on fine-needle aspiration (FNA) or core needle biopsy. Recurrent mutations in EED and SUZ12, which encode subunits of polycomb repressive complex 2… read more here.
Keywords: biopsy; malignant peripheral; loss; h3k27me3 ... See more keywords
RARE-20. MALIGNANT PERIPHERAL NERVE SHEATH TUMOR OF A CRANIAL NERVE IN AN INFANT WITH NEUROCUTANEOUS MELANOSIS
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.731
Abstract: Abstract At one month of age, a female presented with a giant congenital nevus along lower back and thighs and hydrocephalus. A ventriculoperitoneal shunt was placed. An MRI was done at six months, initially reported… read more here.
Keywords: cranial nerve; malignant peripheral; neurocutaneous melanosis; nerve sheath ... See more keywords
Morbidity and Function Loss After Resection of Malignant Peripheral Nerve Sheath Tumors.
Sign Up to like & getrecommendations! Published in 2021 at "Neurosurgery"
DOI: 10.1093/neuros/nyab342
Abstract: BACKGROUND Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas. Their resection may lead to serious morbidity. Incidence of postoperative motor and sensory deficits is unknown, and reconstruction aimed at restoring such deficits… read more here.
Keywords: malignant peripheral; morbidity; peripheral nerve; resection ... See more keywords