Impact of the Nuclear Envelope on Malignant Transformation, Motility, and Survival of Lung Cancer Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced science"
DOI: 10.1002/advs.202102757
Abstract: Nuclear pore complexes (NPCs) selectively mediate all nucleocytoplasmic transport and engage in fundamental cell-physiological processes. It is hypothesized that NPCs are critical for malignant transformation and survival of lung cancer cells, and test the hypothesis… read more here.
Keywords: malignant transformation; cancer cells; survival; lung cancer ... See more keywords
circCIMT Silencing Promotes Cadmium‐Induced Malignant Transformation of Lung Epithelial Cells Through the DNA Base Excision Repair Pathway (Adv. Sci. 14/2023)
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202206896
Abstract: Malignant Transformation of Cells Cadmium (Cd) exposure derived from air pollution and smoking may cause lung cancer. In article number 2206896, Lihua Huang, Yiguo Jiang, and co‐workers reveal the mechanism of the role of circRNA… read more here.
Keywords: transformation lung; lung; lung epithelial; malignant transformation ... See more keywords
TWEAK Signaling-Induced ID1 Expression Drives Malignant Transformation of Hepatic Progenitor Cells During Hepatocarcinogenesis.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300350
Abstract: The malignant transformation of hepatic progenitor cells (HPCs) in the inflammatory microenvironment is the root cause of hepatocarcinogenesis. However, the potential molecular mechanisms are still elusive. The HPCs subgroup is identified by single-cell RNA (scRNA)… read more here.
Keywords: hepatic progenitor; expression; transformation hepatic; progenitor cells ... See more keywords
MYC‐driven malignant transformation of mature murine B cells requires inhibition of both intrinsic apoptosis and p53 activity
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Immunology"
DOI: 10.1002/eji.201847585
Abstract: Increased expression of the oncogene MYC is a common feature of many B‐cell malignancies, however MYC overexpression by itself is not sufficient for transformation, and additional genetic events are required, although the exact nature of… read more here.
Keywords: malignant transformation; murine cells; transformation; expression ... See more keywords
Accuracy of narrow‐band imaging for diagnosing malignant transformation of vocal cord leukoplakia: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2023 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.1049
Abstract: To explore whether narrow‐band imaging (NBI) endoscopy is accurate in the diagnosis of malignant transformation of vocal cord leukoplakia. read more here.
Keywords: band imaging; cord leukoplakia; narrow band; malignant transformation ... See more keywords
A clinical signature predicting the malignant transformation of inflammatory myofibroblastic tumor in the head and neck
Sign Up to like & getrecommendations! Published in 2022 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.731
Abstract: Inflammatory myofibroblastic tumors in the head and neck (HNIMTs) sometimes show aggressive clinical features and can be diagnosed as HNIMT with malignant transformation. read more here.
Keywords: signature predicting; head neck; clinical signature; inflammatory myofibroblastic ... See more keywords
Effect of mir‐92a‐3p on hydroquinone induced changes in human lymphoblastoid cell cycle and apoptosis
Sign Up to like & getrecommendations! Published in 2023 at "Environmental Toxicology"
DOI: 10.1002/tox.23775
Abstract: Hydroquinone (HQ), one of the metabolites of benzene in humans, has significant hepatotoxic properties. Chronic exposure to HQ can lead to leukemia. In a previous study by this group, we constructed a model of malignant… read more here.
Keywords: malignant transformation; cell; mir 92a; cell cycle ... See more keywords
Genomic profile of a primary squamous cell carcinoma arising from malignant transformation of a pineal epidermoid cyst
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-019-03983-5
Abstract: Malignant transformation of intracranial epidermoid cysts is a rare occurrence. We present the second case of such an event occurring in the pineal region and the first case sent for detailed genomic profiling. MRI demonstrated… read more here.
Keywords: cell carcinoma; squamous cell; malignant transformation; cyst ... See more keywords
Malignant transformation of oral leukoplakia: a follow-up study
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Oral Investigations"
DOI: 10.1007/s00784-020-03322-4
Abstract: Objective The main objective of the study was to identify the determinants that contribute to the malignant transformation of oral leukoplakia in a group of patients managed in secondary care. A secondary objective was to… read more here.
Keywords: transformation oral; oral leukoplakia; malignant transformation; transformation ... See more keywords
Oral tongue leukoplakia: analysis of clinicopathological characteristics, treatment outcomes, and factors related to recurrence and malignant transformation
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DOI: 10.1007/s00784-020-03735-1
Abstract: Objectives The tongue is identified as a high-risk site for oral leukoplakia and malignant transformation. The purpose of this study is to investigate the clinicopathological characteristics and treatment outcomes of tongue leukoplakia and assess the… read more here.
Keywords: tongue leukoplakia; recurrence malignant; malignant transformation; transformation ... See more keywords
Binary and WHO dysplasia grading systems for the prediction of malignant transformation of oral leukoplakia and erythroplakia: a systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical oral investigations"
DOI: 10.1007/s00784-021-04008-1
Abstract: OBJECTIVES The aim of this systematic review was to examine the evidence of the binary histologic grading system capacity for predicting malignant transformation and to compare it with that of the WHO systems. MATERIAL AND… read more here.
Keywords: grading systems; system; systematic review; malignant transformation ... See more keywords