Diastereoselective hydrolysis of branched malonate diesters by Porcine Liver Esterase: Synthesis of 5‐benzyl substituted Cα‐methyl‐β‐proline and catalytic evaluation
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DOI: 10.1002/ejoc.201700605
Abstract: Malonate diesters with highly branched side chains containing a preexisting chiral center were prepared from optically pure amino alcohols and subjected to asymmetric enzymatic hydrolysis by Porcine Liver Esterase (PLE). Recombinant PLE isoenzymes have been… read more here.
Keywords: methyl proline; malonate diesters; substituted methyl; hydrolysis ... See more keywords