Articles with "malononitrile dimer" as a keyword



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Malononitrile dimer as a privileged reactant in design and skeletal diverse synthesis of heterocyclic motifs

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Published in 2017 at "Molecular Diversity"

DOI: 10.1007/s11030-017-9807-y

Abstract: Malononitrile dimer as a precursor reactant has been extensively applied in the diversity-oriented synthesis of various heterocyclic motifs, bis-heterocyclic compounds, fused heterocycle derivatives, bicyclic bridged heterocyclic scaffolds, and highly substituted carbocyclic compounds. These remarkable products… read more here.

Keywords: dimer privileged; chemistry; malononitrile dimer; heterocyclic motifs ... See more keywords
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Pot, atom and step economic (PASE) assembly of salicylaldehydes, malononitrile dimer and 4-hydroxypyridine-2(1H)-ones into medicinally relevant 5H-chromeno[2,3-b]pyridine scaffold

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Published in 2019 at "Molecular Diversity"

DOI: 10.1007/s11030-019-09968-x

Abstract: The new multicomponent reaction (MCR) has been found: one-pot selective and efficient formation of the new 5-(4-hydroxy-2-oxo-1,2-dihydropyridin-3-yl)-substituted 5H-chromeno[2,3-b]pyridines in 61–97% yields directly from simple and easily available salicylaldehydes, malononitrile dimer and 4-hydroxypyridine-2(1H)-ones in small amount… read more here.

Keywords: hydroxypyridine ones; pyridine; dimer hydroxypyridine; chromeno pyridine ... See more keywords