Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma.
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DOI: 10.1021/acs.jmedchem.1c00466
Abstract: Development of mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) inhibitors is of great value and significance in the treatment of neoplastic disorders and inflammatory and autoimmune diseases. However, there is a lack of effective… read more here.
Keywords: cell; cell lymphoma; high throughput; based malt1 ... See more keywords
A patent review of MALT1 inhibitors (2013-present).
Sign Up to like & getrecommendations! Published in 2021 at "Expert opinion on therapeutic patents"
DOI: 10.1080/13543776.2021.1951703
Abstract: INTRODUCTION MALT1 is the only human paracaspase, a protease with unique cleavage activity and substrate specificity. As a key regulator of immune responses, MALT1 has attracted attention as an immune modulatory target for the treatment… read more here.
Keywords: patent review; review malt1; malt1; inhibitors 2013 ... See more keywords