Systematic In‐Depth Proteomic Analysis of Mitochondria‐Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes
Sign Up to like & getrecommendations! Published in 2018 at "PROTEOMICS"
DOI: 10.1002/pmic.201700478
Abstract: Mitochondria‐associated endoplasmic reticulum membranes (MAMs) regulate important cellular functions including calcium signaling, bioenergetics, and apoptosis during neurodevelopment and carcinogenesis, but its function in male reproduction and spermatogenesis remains enigmatic because the field lacks a complete… read more here.
Keywords: endoplasmic reticulum; analysis; associated endoplasmic; mitochondria associated ... See more keywords
DISC1 Modulates Neuronal Stress Responses by Gate-Keeping ER-Mitochondria Ca2+ Transfer through the MAM.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.11.043
Abstract: A wide range of Ca2+-mediated functions are enabled by the dynamic properties of Ca2+, all of which are dependent on the endoplasmic reticulum (ER) and mitochondria. Disrupted-in-schizophrenia 1 (DISC1) is a scaffold protein that is… read more here.
Keywords: stress; ca2; mitochondria ca2; mam ... See more keywords
Modulation of physicochemical properties of magnetic agarose microspheres by hydrolysis-suppressive sequential crosslinking
Sign Up to like & getrecommendations! Published in 2021 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2021.127607
Abstract: Abstract Separation and purification of target proteins are essential for drug discovery and development. A magnetic separation has been exploited due to its high efficiency. Despite many studies on chemical crosslinking of a magnetic agarose… read more here.
Keywords: sequential crosslinking; crosslinked mam; ech; magnetic agarose ... See more keywords
Disruption of the mitochondria‐associated ER membrane (MAM) plays a central role in palmitic acid–induced insulin resistance
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2017.08.006
Abstract: &NA; The mitochondria‐associated ER membrane (MAM) is a specialized subdomain of ER that physically connects with mitochondria. Although disruption of inter‐organellar crosstalk via the MAM impairs cellular homeostasis, its pathological significance in insulin resistance in… read more here.
Keywords: mam; mitochondria associated; acid; insulin resistance ... See more keywords
α7 Nicotinic receptor-modulating agents reverse the hyperdopaminergic tone in the MAM model of schizophrenia
Sign Up to like & getrecommendations! Published in 2018 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-018-0066-0
Abstract: Recent evidence has emerged supporting a role for the cholinergic system in schizophrenia, including the potential of α7 modulators as a treatment strategy. However, preclinical studies to date have relied on studies in normal systems… read more here.
Keywords: mam; hyperdopaminergic tone; tone mam; model schizophrenia ... See more keywords
MDGA1 negatively regulates amyloid precursor protein–mediated synapse inhibition in the hippocampus
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2115326119
Abstract: Significance This study demonstrates a universal synaptic mechanism responsible for tuning GABAergic neural circuit strength and turnover. These observations are relevant to the issue of neural circuit dynamics, which have only been investigated in certain… read more here.
Keywords: mdga1; amyloid precursor; inhibition; mam ... See more keywords
Thermoresponsive polymer gated and superparamagnetic nanoparticles embedded hollow mesoporous silica nanoparticles as smart multifunctional nanocarrier for targeted and controlled delivery of doxorubicin.
Sign Up to like & getrecommendations! Published in 2020 at "Nanotechnology"
DOI: 10.1088/1361-6528/ab8b0e
Abstract: Design and development of drug delivery nanocarriers with high loading capacity, excellent biocompatibility, targeting ability and controllability have been the ultimate goal of the biomedical research community. In this work, we have reported synthesis and… read more here.
Keywords: delivery; mesoporous silica; nipam mam; hmsio2 nipam ... See more keywords
Liposuction‐Augmentation Mammaplasty
Sign Up to like & getrecommendations! Published in 2018 at "Aesthetic Surgery Journal"
DOI: 10.1093/asj/sjx174
Abstract: Background: The female breast loses superior fullness and becomes more ptotic over time. Women often present to their plastic surgeon requesting reversal of this evolution. While liposuction alone has been proven to lift the breast,… read more here.
Keywords: mam; breast; augmentation; augmentation mammaplasty ... See more keywords
Biomarkers of Environmental Enteric dDsfunction (EED) Predict Growth and Recovery Among Children with Moderate Acute Malnutrition (MAM) in Sierra Leone
Sign Up to like & getrecommendations! Published in 2020 at "Current Developments in Nutrition"
DOI: 10.1093/cdn/nzaa054_153
Abstract: The objectives of the study were to 1) develop an EED score using fecal host mRNA transcripts, 2) compare three EED biomarkers, and 3) examine associations between EED biomarkers and growth outcomes and recovery from… read more here.
Keywords: recovery; mrna transcripts; mam; score ... See more keywords
T180. REDUCED [3H]RO15-4513 RECEPTOR BINDING IN THE VENTRAL HIPPOCAMPUS IN THE MAM DEVELOPMENTAL DISRUPTION MODEL OF SCHIZOPHRENIA
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbaa029.740
Abstract: Abstract Background Post-mortem studies in schizophrenia patients have repeatedly found abnormalities in the γ-aminobutyric acid (GABA) inhibitory neurotransmission system in the form of parvalbumin (PV)-expressing GABAergic interneuron reduction and aberrant glutamic acid decarboxylase mRNA expression… read more here.
Keywords: schizophrenia; mam; receptor; ventral hippocampus ... See more keywords
Barriers to Management of Moderate Acute Malnutrition Among Children Aged 6 to 59 Months in Damot Pulassa, Wolaita, South Ethiopia: A Phenomenological Study of Mothers and Health Service Providers.
Sign Up to like & getrecommendations! Published in 2022 at "Food and nutrition bulletin"
DOI: 10.1177/03795721221088817
Abstract: BACKGROUND Management of children with moderate acute malnutrition (MAM) needs to improve to reduce the transition from MAM to severe acute malnutrition (SAM). OBJECTIVE This study aimed to assess barriers to management of MAM among… read more here.
Keywords: food; acute malnutrition; children aged; service ... See more keywords