Engineering new neurons: in vivo reprogramming in mammalian brain and spinal cord
Sign Up to like & getrecommendations! Published in 2017 at "Cell and Tissue Research"
DOI: 10.1007/s00441-017-2729-2
Abstract: Neurons are postmitotic. Once lost because of injury or degeneration, they do not regenerate in most regions of the mammalian central nervous system. Recent advancements nevertheless clearly reveal that new neurons can be reprogrammed from… read more here.
Keywords: mammalian brain; brain spinal; new neurons; spinal cord ... See more keywords
RNAseq profiling of primary microglia and astrocyte cultures in near-term ovine fetus: A glial in vivo-in vitro multi-hit paradigm in large mammalian brain
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2016.11.008
Abstract: BACKGROUND The chronically instrumented fetal sheep is a widely used animal model to study fetal brain development in health and disease, but no methods exist yet to interrogate dedicated brain cell populations to identify their… read more here.
Keywords: large mammalian; near term; astrocyte cultures; mammalian brain ... See more keywords
jULIEs: nanostructured polytrodes for low traumatic extracellular recordings and stimulation in the mammalian brain
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neural Engineering"
DOI: 10.1088/1741-2552/ac514f
Abstract: Objective. Extracellular microelectrode techniques are the most widely used approach to interrogate neuronal populations. However, regardless of the manufacturing method used, damage to the vasculature and circuit function during probe insertion remains a concern. This… read more here.
Keywords: polytrodes low; nanostructured polytrodes; mammalian brain; brain ... See more keywords
SRF Is Required for Maintenance of Astrocytes in Non-Reactive State in the Mammalian Brain
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DOI: 10.1523/eneuro.0447-19.2020
Abstract: Abstract Astrocytes play several critical roles in the normal functioning of the mammalian brain, including ion homeostasis, synapse formation, and synaptic plasticity. Following injury and infection or in the setting of neurodegeneration, astrocytes become hypertrophic… read more here.
Keywords: reactive state; mammalian brain; non reactive; srf ... See more keywords