The first structure of an active mammalian dCTPase and its complexes with substrate analogues and products.
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DOI: 10.1016/j.jmb.2020.01.005
Abstract: Precise regulation of dNTPs within the cellular nucleotide pool is essential for high accuracy of DNA replication and is critical for retaining the genomic integrity. Recently, human dCTPase (deoxycytidine triphosphatase), also known as DCTPP1 (human… read more here.
Keywords: mammalian dctpase; first structure; structure active; dctpase ... See more keywords