A review on Tsukushi: mammalian development, disorders, and therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cell communication and signaling"
DOI: 10.1007/s12079-022-00669-z
Abstract: Tsukushi (TSK), a leucine-rich peptidoglycan in the extracellular compartment, mediates multiple signaling pathways that are critical for development and metabolism. TSK regulates signaling pathways that eventually control cellular communication, proliferation, and cell fate determination. Research… read more here.
Keywords: development; review tsukushi; development disorders; mammalian development ... See more keywords
Understanding the Mechanobiology of Early Mammalian Development through Bioengineered Models.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental cell"
DOI: 10.1016/j.devcel.2019.02.024
Abstract: Research in developmental biology has been recently enriched by a multitude of in vitro models recapitulating key milestones of mammalian embryogenesis. These models obviate the challenge posed by the inaccessibility of implanted embryos, multiply experimental opportunities,… read more here.
Keywords: mammalian development; understanding mechanobiology; mechanobiology early; development bioengineered ... See more keywords
Epigenome in Early Mammalian Development: Inheritance, Reprogramming and Establishment.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2017.10.008
Abstract: Drastic epigenetic reprogramming takes place during preimplantation development, leading to the conversion of terminally differentiated gametes to a totipotent embryo. Deficiencies in remodeling of the epigenomes can cause severe developmental defects, including embryonic lethality. However,… read more here.
Keywords: mammalian development; development inheritance; inheritance reprogramming; epigenome early ... See more keywords
Differential requirements for Tousled-like kinases 1 and 2 in mammalian development
Sign Up to like & getrecommendations! Published in 2017 at "Cell Death and Differentiation"
DOI: 10.1038/cdd.2017.108
Abstract: The regulation of chromatin structure is critical for a wide range of essential cellular processes. The Tousled-like kinases, TLK1 and TLK2, regulate ASF1, a histone H3/H4 chaperone, and likely other substrates, and their activity has… read more here.
Keywords: mammalian development; tlk2; like kinases; tousled like ... See more keywords
Symmetry Breaking in the Mammalian Embryo.
Sign Up to like & getrecommendations! Published in 2018 at "Annual review of cell and developmental biology"
DOI: 10.1146/annurev-cellbio-100617-062616
Abstract: We present an overview of symmetry breaking in early mammalian development as a continuous process from compaction to specification of the body axes. While earlier studies have focused on individual symmetry-breaking events, recent advances enable… read more here.
Keywords: mammalian development; breaking mammalian; mammalian embryo; symmetry breaking ... See more keywords
Transcriptome of the parasitic flatworm Schistosoma mansoni during intra-mammalian development
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0007743
Abstract: Schistosomes are parasitic blood flukes that survive for many years within the mammalian host vasculature. How the parasites establish a chronic infection in the hostile bloodstream environment, whilst evading the host immune response is poorly… read more here.
Keywords: intra mammalian; mammalian development; schistosoma mansoni; host ... See more keywords