Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase.
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DOI: 10.1021/acs.jmedchem.8b01000
Abstract: The glycolytic enzyme aldolase is an emerging drug target in diseases such as cancer and protozoan infections which are dependent on a hyperglycolytic phenotype to synthesize adenosine 5'-triphosphate and metabolic precursors for biomass production. To… read more here.
Keywords: aldolase; inhibitors mammalian; mammalian glycolytic; bisphosphonate ... See more keywords