Cardiac injury of the newborn mammalian heart accelerates cardiomyocyte terminal differentiation
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DOI: 10.1038/s41598-017-08947-2
Abstract: After birth cardiomyocytes undergo terminal differentiation, characterized by binucleation and centrosome disassembly, rendering the heart unable to regenerate. Yet, it has been suggested that newborn mammals regenerate their hearts after apical resection by cardiomyocyte proliferation.… read more here.
Keywords: newborn mammalian; terminal differentiation; heart; apical resection ... See more keywords
Filamin C is Essential for mammalian myocardial integrity
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DOI: 10.1371/journal.pgen.1010630
Abstract: FLNC, encoding filamin C, is one of the most mutated genes in dilated and hypertrophic cardiomyopathy. However, the precise role of filamin C in mammalian heart remains unclear. In this study, we demonstrated Flnc global… read more here.
Keywords: mammalian heart; essential mammalian; heart; mammalian myocardial ... See more keywords
Histamine can be Formed and Degraded in the Human and Mouse Heart
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.582916
Abstract: Histamine is metabolized by several enzymes in vitro and in vivo. The relevance of this metabolism in the mammalian heart in vivo is unclear. However, histamine can exert positive inotropic effects (PIE) and positive chronotropic… read more here.
Keywords: formed degraded; histamine formed; heart; histamine ... See more keywords