Disruption of O‐GlcNAc homeostasis during mammalian oocyte meiotic maturation impacts fertilization
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23131
Abstract: Meiotic maturation and fertilization are metabolically demanding processes, and thus the mammalian oocyte is highly susceptible to changes in nutrient availability. O‐GlcNAcylation—the addition of a single sugar residue (O‐linked β‐N‐acetylglucosamine) on proteins—is a posttranslational modification… read more here.
Keywords: fertilization; meiotic maturation; glcnac homeostasis; maturation ... See more keywords
Translational Regulation in the Mammalian Oocyte.
Sign Up to like & getrecommendations! Published in 2017 at "Results and problems in cell differentiation"
DOI: 10.1007/978-3-319-60855-6_12
Abstract: Fully grown oocytes arrest meiosis at prophase I and deposit maternal RNAs. A subset of maternal transcripts is stored in a dormant state in the oocyte, and the timely driven translation of specific mRNAs guides… read more here.
Keywords: regulation mammalian; progression; mammalian oocyte; translational regulation ... See more keywords