Mammalian synthetic biology in the age of genome editing and personalized medicine.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2017.06.003
Abstract: The recent expansion of molecular tool kits has propelled synthetic biology toward the design of increasingly sophisticated mammalian systems. Specifically, advances in genome editing, protein engineering, and circuitry design have enabled the programming of cells… read more here.
Keywords: medicine; genome editing; synthetic biology; biology ... See more keywords
Mammalian synthetic biology by CRISPRs engineering and applications.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2019.05.020
Abstract: Technologies harnessing CRISPR systems have been rapidly evolving and expanding the capacity of researchers for understanding of mammalian cell behavior and its underlying mechanisms through genome and epigenome manipulations. In this review, we summarized the… read more here.
Keywords: engineering; synthetic biology; crisprs engineering; biology ... See more keywords
Genetic Toolkits to Design and Build Mammalian Synthetic Systems.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2020.12.007
Abstract: Construction of DNA-encoded programs is central to synthetic biology and the chosen method often determines the time required to design and build constructs for testing. Here, we describe and summarise key features of the available… read more here.
Keywords: toolkits design; design; build mammalian; mammalian synthetic ... See more keywords