Abstract 5255: Comparison of high-fructose and standard diets in methylnitrosourea (MNU)-induced ER+mammary cancers: Altered carcinogenesis, differential effects of metformin, and metabolomic differences
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DOI: 10.1158/1538-7445.am2017-5255
Abstract: The MNU-induced model of ER+ mammary cancers in Sprague-Dawley rats has routinely been employed in screening for chemopreventive agents. We recently reported that metformin was ineffective in preventing mammary cancers in rats on a standard… read more here.
Keywords: mammary cancers; vehicle; high fructose; mnu ... See more keywords