Epigenetic dysregulation of key developmental genes in radiation‐induced rat mammary carcinomas
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31309
Abstract: With the increase in the number of long‐term cancer survivors worldwide, there is a growing concern about the risk of secondary cancers induced by radiotherapy. Epigenetic modifications of genes associated with carcinogenesis are attractive targets… read more here.
Keywords: radiation induced; dysregulation; mammary carcinomas; carcinomas ... See more keywords
Evaluation of immunohistopathological profile of tubular and solid canine mammary carcinomas.
Sign Up to like & getrecommendations! Published in 2021 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2021.02.004
Abstract: Breast cancer is the most common cancer in women, but the incidence of mammary carcinoma in female dogs is even higher than in humans. These two tumors have similarities that can be seen by its… read more here.
Keywords: carcinoma; microscopy; mammary carcinomas; tubular solid ... See more keywords
Centrosome Abnormalities and Polyploidy in Murine Mammary Carcinomas with Different Degrees of Hormone Responsiveness
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DOI: 10.1080/07357907.2020.1766482
Abstract: Abstract Centrosome amplification leads to aberrant mitosis, giving rise to aneuploidy and it has been associated with poor prognosis in human cancers. This study aimed to evaluate the relationship between polyploidy, centrosome abnormalities, and response… read more here.
Keywords: mammary carcinomas; abnormalities polyploidy; centrosome abnormalities; polyploidy murine ... See more keywords
Neutrophil-to-Lymphocyte ratio (NLR) is an independent prognostic marker for feline mammary carcinomas.
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary and comparative oncology"
DOI: 10.1111/vco.12686
Abstract: Blood leukocyte counts and respective derived ratios have been described as potential prognostic markers in several tumours in veterinary oncology. This study aimed to evaluate peripheral blood leukocyte subpopulations and NLR as prognostic factors for… read more here.
Keywords: nlr independent; mammary carcinomas; independent prognostic; feline mammary ... See more keywords
HER2 Amplification Status in Feline Mammary Carcinoma: A Tissue Microarray–Fluorescence In Situ Hydridization–Based Study
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DOI: 10.1177/0300985818808531
Abstract: Human epidermal growth factor receptor 2 (HER2) is a tyrosine kinase receptor overexpressed in a subset of breast cancer due to HER2 gene amplification. HER2 protein is expressed in feline mammary carcinomas, but little is… read more here.
Keywords: mammary carcinomas; her2; feline mammary; amplification ... See more keywords
Osteopontin expression and its relationship with prognostic biomarkers in canine mammary carcinomas
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DOI: 10.1590/1678-5150-pvb-6489
Abstract: ABSTRACT: Osteopontin is a glycophosphoprotein implicated in different physiologic and pathologic processes and is known to be involved in progression and metastasis of various cancers in humans, but this relation is still little explored in… read more here.
Keywords: canine mammary; mammary carcinomas; expression; carcinomas osteopontin ... See more keywords
Neutron-induced Rat Mammary Carcinomas Are Mainly of Luminal Subtype and Have Multiple Copy Number Aberrations
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DOI: 10.21873/anticanres.13222
Abstract: Background/Aim: Neutrons are used as a type of high linear energy transfer (LET) radiation and they have stronger carcinogenic effects compared to low LET radiation. We sought to clarify the features of mammary carcinomas for… read more here.
Keywords: carcinomas; mammary carcinomas; copy number; number aberrations ... See more keywords
Unfavorable Prognostic Effects of the Stem Cell Pluripotency Factor Sox2 in Feline Invasive Mammary Carcinomas
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2020.622019
Abstract: Background: Sex-determining Region Y (SRY)-box transcription factor-2 (Sox2) belongs to the “Yamanaka's factors,” necessary and sufficient to convert somatic cells into pluripotent stem cells. In breast cancers, Sox2 expression has been associated with poor prognosis,… read more here.
Keywords: invasive mammary; mammary carcinomas; expression; sox2 ... See more keywords