Prolactin regulates RANKL expression via signal transducer and activator of transcription 5a signaling in mammary epithelial cells of dairy cows
Sign Up to like & getrecommendations! Published in 2023 at "Cell Biology International"
DOI: 10.1002/cbin.11988
Abstract: Receptor of activated nuclear factor kappa B ligand (RANKL) is regulated by prolactin in the mammary gland. However, the intrinsic molecular mechanism is not well understood. Herein, mammary epithelial cells (MECs) of dairy cows were… read more here.
Keywords: expression; rankl; epithelial cells; prolactin ... See more keywords
Mechanism of prolactin inhibition of miR‐135b via methylation in goat mammary epithelial cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25925
Abstract: Prolactin is an important endocrine activator of lactogenesis. This study investigated the function and mechanism of miR‐135b in the enhancement of lactation by prolactin in goat mammary epithelial tissue. We utilized S‐Poly (T) sequencing to… read more here.
Keywords: mammary epithelial; prolactin; goat mammary; mir 135b ... See more keywords
PGE2/EP4 Signaling Controls the Transfer of the Mammary Stem Cell State by Lipid Rafts in Extracellular Vesicles
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DOI: 10.1002/stem.2476
Abstract: Prostaglandin E2 (PGE2)‐initiated signaling contributes to stem cell homeostasis and regeneration. However, it is unclear how PGE2 signaling controls cell stemness. This study identifies a previously unknown mechanism by which PGE2/prostaglandin E receptor 4 (EP4)… read more here.
Keywords: extracellular vesicles; state; mammary epithelial; stem cell ... See more keywords
An Organotypic 3D Assay for Primary Human Mammary Epithelial Cells that Recapitulates Branching Morphogenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7021-6_9
Abstract: We have developed a three-dimensional organotypic culture system for primary human mammary epithelial cells (HMECs) in which the cells are cultured in free floating collagen type I gels. In this assay, luminal cells predominantly form… read more here.
Keywords: epithelial cells; mammary epithelial; branching morphogenesis; human mammary ... See more keywords
IFN-γ Activates the TLR4-CCL5 Signaling Through Reducing Arginine Level, Leading to Enhanced Susceptibility of Bovine Mammary Epithelial Cells to Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation"
DOI: 10.1007/s10753-020-01288-9
Abstract: Dairy cow mastitis is a common bacterial infectious disease which seriously threatens the development of the dairy cow industry. Previous studies have found that increased IFN-γ expression in dairy cows makes dairy cows more susceptible… read more here.
Keywords: epithelial cells; mammary epithelial; dairy; bovine mammary ... See more keywords
Menin Modulates Mammary Epithelial Cell Numbers in Bovine Mammary Glands Through Cyclin D1
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Mammary Gland Biology and Neoplasia"
DOI: 10.1007/s10911-017-9385-8
Abstract: Menin, the protein encoded by the MEN1 gene, is abundantly expressed in the epithelial cells of mammary glands. Here, we found MEN1/menin expression slowly decreased with advancing lactation but increased by the end of lactation.… read more here.
Keywords: epithelial cell; mammary epithelial; mammary glands; menin ... See more keywords
Androgen Receptor Signalling Promotes a Luminal Phenotype in Mammary Epithelial Cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Mammary Gland Biology and Neoplasia"
DOI: 10.1007/s10911-018-9406-2
Abstract: Androgens influence mammary gland development but the specific role of the androgen receptor (AR) in mammary function is largely unknown. We identified cell subsets that express AR in vivo and determined the effect of AR… read more here.
Keywords: epithelial cells; mammary epithelial; phenotype mammary; androgen receptor ... See more keywords
Redirecting Normal and Cancer Stem Cells to a Mammary Epithelial Cell Fate
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Mammary Gland Biology and Neoplasia"
DOI: 10.1007/s10911-019-09439-x
Abstract: Tissue microenvironments, also known as stem cell niches, influence not only resident cells but also cells in surrounding tissues. Physical and biochemical intercellular signals originating from resident stem cells or non-stem cells participate in the… read more here.
Keywords: stem cells; mammary epithelial; epithelial cell; cancer ... See more keywords
Intraductal Injection of Lentivirus Vectors for Stably Introducing Genes into Rat Mammary Epithelial Cells in Vivo
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Mammary Gland Biology and Neoplasia"
DOI: 10.1007/s10911-020-09469-w
Abstract: Various retroviral and lentiviral vectors have been used for up-the-teat intraductal injection to deliver markers, oncogenes, and other genes into mammary epithelial cells in mice. These methods along with the large number of genetically engineered… read more here.
Keywords: epithelial cells; mammary epithelial; stably introducing; breast ... See more keywords
Autophagy of bovine mammary epithelial cell induced by intracellular Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Microbiology"
DOI: 10.1007/s12275-020-9182-8
Abstract: Bovine mastitis is a common disease in the dairy industry that causes great economic losses. As the primary pathogen of contagious mastitis, Staphylococcus aureus (S. aureus) can invade bovine mammary epithelial cells, thus evading immune… read more here.
Keywords: staphylococcus aureus; mammary epithelial; intracellular aureus; aureus ... See more keywords
Translin restricts the growth of pubertal mammary epithelial cells estrogen-independently in mice.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.10.176
Abstract: Translin, a ubiquitous RNA/DNA-binding protein that forms a hetero-octamer together with Translin-associated factor X (TRAX), possesses endoribonuclease activity and plays a physiological role in restricting the size and differentiation of mesenchymal precursor cells. However, the… read more here.
Keywords: epithelial cells; mammary epithelial; pubertal mammary; translin null ... See more keywords