Comparison of the biomarkers for targeted therapies in primary extra‐mammary and mammary Paget's disease
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.2820
Abstract: Primary Extra‐mammary Paget's disease (EMPD) is a very rare cutaneous adenocarcinoma affecting anogenital or axillary regions. It is characterized by a prolonged course with recurrences and eventually distant metastatic spread for which no specific therapy… read more here.
Keywords: extra mammary; paget disease; mammary paget; primary extra ... See more keywords
Gene expression and transcriptomic profiles of invasive behavior in extra-mammary Paget's disease
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002296
Abstract: To the Editor: Extra-mammary Paget’s disease (EMPD) is a rare cutaneous intra-epidermal adenocarcinoma with a controversial origin, and frequently occurs in the penoscrotal region in males. Primary EMPD, which originates within the epidermis or apocrine… read more here.
Keywords: extra mammary; disease; mammary paget; transcriptomic profiles ... See more keywords
A monolateral pigmented lesion of the nipple
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Dermatology"
DOI: 10.1111/ced.15361
Abstract: Pigmented mammary Paget's disease is a very rare variant of mammary Paget's disease linked to an underlying carcinoma in almost all cases. We present the case of a 62‐year‐old female patient who came to our… read more here.
Keywords: mammary paget; monolateral pigmented; lesion; lesion nipple ... See more keywords
Immunohistochemical expression of TRPS1 in mammary Paget disease, extramammary Paget disease, and their close histopathologic mimics
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DOI: 10.1111/cup.14414
Abstract: Trichorhinophalangeal syndrome type 1 (TPRS1) expression has been found to be highly sensitive and specific for breast carcinomas. The frequency of TRPS1 expression in cutaneous neoplasms such as mammary Paget disease (MPD) and extramammary PD… read more here.
Keywords: histopathologic mimics; expression; mammary paget; paget ... See more keywords
Keratin 7 and ERBB2 Negative Mammary Paget Disease Without an Underlying in Situ and Invasive Carcinoma
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DOI: 10.1177/10668969221076550
Abstract: We report a unique case of a post-menopausal female who presented with a lesion on the areola. A biopsy of the lesion demonstrated a pagetoid intraepithelial neoplasm suggesting a differential diagnosis of mammary Paget disease… read more here.
Keywords: disease; keratin erbb2; mammary paget; erbb2 negative ... See more keywords
Extra-mammary Paget’s disease (EMPD) of the skin: A comprehensive genomic profiling (CGP) study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.9591
Abstract: 9591 Background: EMPD is an intraepidermal adenocarcinoma which frequently progresses into invasive/metastatic disease. Methods: 29 EMPD underwent hybrid-capture based CGP to evaluate all classes of genomic alterations (GA). Tumor mutational burden (TMB) was determined on… read more here.
Keywords: empd; disease; mammary paget; paget disease ... See more keywords