Effects of thyroxine on apoptosis and proliferation of mammary tumors
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2021.111454
Abstract: Hypothyroidism is a protective factor against breast cancer but long-term exposure or overdoses of thyroid replacement therapy with thyroxine (T4) may increase breast cancer risk. OBJECTIVE to study, in vivo and in vitro, the effects… read more here.
Keywords: hypothyroidism; apoptosis; mammary tumors; apoptosis proliferation ... See more keywords
MUC1 triggers lineage plasticity of Her2 positive mammary tumors
Sign Up to like & getrecommendations! Published in 2022 at "Oncogene"
DOI: 10.1038/s41388-022-02320-y
Abstract: Aberrant overexpression of mucin 1 (MUC1) and human epidermal growth factor receptor 2 (HER2) are often observed in breast cancer. However, the role of concomitant MUC1/HER2 in the development of breast cancer has not been… read more here.
Keywords: muc1; lineage plasticity; breast cancer; muc1 her2 ... See more keywords
Polymorphism of glutathione S-transferase P1 of dogs with mammary tumors.
Sign Up to like & getrecommendations! Published in 2023 at "Veterinary and comparative oncology"
DOI: 10.1111/vco.12885
Abstract: Mammary tumors constitute more than half of neoplasms in female dogs from different countries. Genome sequences are associated with cancer susceptibility but there is little information available about genetic polymorphisms of glutathione S-transferase P1 (GSTP1)… read more here.
Keywords: female dogs; glutathione transferase; dogs mammary; mammary tumors ... See more keywords
Mammary tumors in Sprague Dawley rats induced by N-ethyl-N-nitrosourea for evaluating terahertz imaging of breast cancer
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Imaging"
DOI: 10.1117/1.jmi.8.2.023504
Abstract: Abstract. Purpose: The objective of this study is to quantitatively evaluate terahertz (THz) imaging for differentiating cancerous from non-cancerous tissues in mammary tumors developed in response to injection of N-ethyl-N-nitrosourea (ENU) in Sprague Dawley rats.… read more here.
Keywords: dawley rats; sprague dawley; mammary tumors; cancerous tissues ... See more keywords
L1 TGF-beta blocks type I IFN release and tumor rejection in spontaneous mammary tumors
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-itoc7.1
Abstract: Background Activation of the STimulator of INterferon Genes (STING) by DMXAA (5,6-dimethylxanthenone-4-acetic acid) can induce a strong production of IFNα/β and the rejection of transplanted primary tumors. However, the efficacy of such therapeutic approach for… read more here.
Keywords: none; type ifn; tgf; tumor ... See more keywords
Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-16-1735
Abstract: Purpose: Whether it is safe for estrogen receptor–positive (ER+) patients with breast cancer to consume soy isoflavone genistein remains controversial. We compared the effects of genistein intake mimicking either Asian (lifetime) or Caucasian (adulthood) intake… read more here.
Keywords: lifetime genistein; response; genistein; mammary tumors ... See more keywords
Consensus for the diagnosis, prognosis and treatment of feline mammary tumors
Sign Up to like & getrecommendations! Published in 2018 at "Brazilian Journal of Veterinary Research and Animal Science"
DOI: 10.11606/issn.1678-4456.bjvras.2018.135084
Abstract: Mammary neoplasms are described as the third most common type of feline tumor, after haematopoietic and skin tumors, and present a challenge for clinicians because the prognosis for feline mammary tumors ranges from guarded to… read more here.
Keywords: prognosis treatment; mammary tumors; treatment feline; feline mammary ... See more keywords
Epitheliosis is a histopathological finding associated with malignancy and poor prognosis in dogs with mammary tumors.
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary pathology"
DOI: 10.1177/03009858221092013
Abstract: Canine mammary epitheliosis (ME) is a poorly studied dysplasia that may have premalignant potential. In this study, the clinicopathological relevance of ME was prospectively studied in 90 female dogs with mammary tumors (MTs) that underwent… read more here.
Keywords: epitheliosis histopathological; histopathological finding; finding associated; dogs mammary ... See more keywords
Usefulness of cytologic criteria in ultrasound-guided fine-needle aspirates from subcentimeter canine mammary tumors
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Veterinary Diagnostic Investigation"
DOI: 10.1177/1040638717718886
Abstract: We determined cytologic features of histologically confirmed subcentimeter canine mammary tumors (CMTs) to determine reasonable criteria for an accurate cytologic diagnosis. Fifty-three CMTs from 28 bitches were included. All cytologic samples were collected by ultrasound-guided… read more here.
Keywords: guided fine; canine mammary; mammary tumors; ultrasound guided ... See more keywords
Estrogen receptors genotypes and canine mammary neoplasia
Sign Up to like & getrecommendations! Published in 2019 at "BMC Veterinary Research"
DOI: 10.1186/s12917-019-2062-y
Abstract: BackgroundEstrogens are essential for the development and proper function of several hormone-dependent organs. There are, however, several lines of evidence associating estrogens with mammary carcinogenesis. A marked individual genetic variability concerning estrogens biosynthesis, metabolism and… read more here.
Keywords: receptors genotypes; canine mammary; mammary neoplasia; mammary tumors ... See more keywords
Diagnostic efficacy of smear cytology and Robinson’s cytological grading of canine mammary tumors with respect to histopathology, cytomorphometry, metastases and overall survival
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0191595
Abstract: Cytology is a simple, rapid, and inexpensive method used for pre-operative diagnosis of canine mammary tumors (CMTs) in veterinary practice. Studies related to human breast cancer showed the Robinson’s grading system—established for invasive ductal carcinoma,… read more here.
Keywords: canine mammary; mammary tumors; histopathology; robinson ... See more keywords