Lesion of the Locus Coeruleus Damages Learning and Memory Performance in Paraquat and Maneb-induced Mouse Parkinson’s Disease Model
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2019.09.006
Abstract: The damage of locus coeruleus (LC) noradrenergic neurons and associated with norepinephrine (NE) depletion are early events in Parkinson's disease (PD). Previous study showed that LC/NE neurodegeneration exacerbates dopaminergic neurotoxicity and motor deficits. However, whether… read more here.
Keywords: paraquat maneb; maneb induced; induced mouse; learning memory ... See more keywords
Exposure to the environmentally toxic pesticide maneb induces Parkinson's disease-like neurotoxicity in mice: A combined proteomic and metabolomic analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Chemosphere"
DOI: 10.2139/ssrn.4091454
Abstract: Maneb is a typical dithiocarbamate fungicide that has been extensively used worldwide. Epidemiological evidence shows that exposure to maneb is an environmental risk factor for Parkinson's disease (PD). However, the mechanisms underlying maneb-induced neurotoxicity have… read more here.
Keywords: maneb induced; parkinson disease; maneb; analysis ... See more keywords