Modeling of thermal degradation kinetics of the C-glucosyl xanthone mangiferin in an aqueous model solution as a function of pH and temperature and protective effect of honeybush extract matrix.
Sign Up to like & getrecommendations! Published in 2018 at "Food research international"
DOI: 10.1016/j.foodres.2017.10.020
Abstract: Mangiferin, a C-glucosyl xanthone, abundant in mango and honeybush, is increasingly targeted for its bioactive properties and thus to enhance functional properties of food. The thermal degradation kinetics of mangiferin at pH3, 4, 5, 6… read more here.
Keywords: degradation; temperature; model; reaction ... See more keywords
Mangiferin antagonizes TNF‐&agr;‐mediated inflammatory reaction and protects against dermatitis in a mice model
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.02.014
Abstract: &NA; This study aimed to investigate whether mangiferin played a protective role in a well‐established dermatitis mouse model and tumor necrosis factor alpha (TNF‐&agr;)‐induced RAW264.7 macrophages. Contact dermatitis is an inflammatory skin disease in the… read more here.
Keywords: inflammatory reaction; tnf agr; inflammation; dermatitis mice ... See more keywords
Protective effect of mangiferin on myocardial ischemia-reperfusion injury in streptozotocin-induced diabetic rats: role of AGE-RAGE/MAPK pathways
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42027
Abstract: Hyperglycemia induced advanced glycation end products-receptor for advanced glycation end products (AGE-RAGE) activation is thought to involve in the development of cardiovascular disease in diabetics. Activation of AGE-RAGE axis results in the oxidative stress and… read more here.
Keywords: diabetic rats; injury; age rage; mangiferin ... See more keywords
The management of diabetes mellitus by mangiferin: advances and prospects.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d1nr06690k
Abstract: Diabetes mellitus has become one of the most challenging public health problems today. There are still various deficiencies that remain in existing therapeutic drugs. With increasing prevalence and mortality rates, more effective therapeutic agents are… read more here.
Keywords: advances prospects; management diabetes; mangiferin; diabetes mellitus ... See more keywords
Recombinant production, purification, and biochemical characterization of a novel L-lactate dehydrogenase from Bacillus cereus NRC1 and inhibition study of mangiferin
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1165465
Abstract: Lactate dehydrogenase (LDH, EC 1.1.1.27) is one of the vital glycolytic conditions, especially during anaerobic conditions. It is a significant diagnostic, prognostic, and monitoring biomarker parameter. A 950-bp DNA fragment containing the gene (LDH) encoding… read more here.
Keywords: mangiferin; bacillus cereus; lactate dehydrogenase; cereus nrc1 ... See more keywords
Design of Nanotechnological Carriers for Ocular Delivery of Mangiferin: Preformulation Study
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27041328
Abstract: (1) Background: Mangiferin (MGN) is a natural compound, showing anti-inflammatory and antioxidant activities for the potential treatment of eye diseases. The poor physicochemical features of MGN (low solubility and high instability) justify its nanoencapsulation into… read more here.
Keywords: mangiferin; ocular delivery; mgn nlc; design nanotechnological ... See more keywords
Mangiferin-Loaded Smart Gels for HSV-1 Treatment
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DOI: 10.3390/pharmaceutics13091323
Abstract: Infections due to HSV-1 affect many people all over the world. To counteract this pathology, usually characterized by perioral sores or by less frequent serious symptoms including keratitis, synthetic antiviral drugs are employed, such as… read more here.
Keywords: hsv treatment; mangiferin loaded; loaded smart; smart gels ... See more keywords
The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15061568
Abstract: Formaldehyde (FA) has been found to induce major Alzheimer’s disease (AD)-like features including cognitive impairment, Aβ deposition, and Tau hyperphosphorylation, suggesting that it may play a significant role in the initiation and progression of AD.… read more here.
Keywords: mangiferin; effect; damage; formaldehyde ... See more keywords
Mangiferin induces islet regeneration in aged mice through regulating p16INK4a
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DOI: 10.3892/ijmm.2018.3524
Abstract: Previous studies by our group on mangiferin demonstrated that it exerts an antihyperglycemic effect through the regulation of cell cycle proteins in 3-month-old, partially pancreatectomized (PPx) mice. However, β-cell proliferation is known to become severely… read more here.
Keywords: mangiferin treatment; cell; aged mice; mangiferin ... See more keywords
Microwave Supported Extraction and Optimization of Flavonoid Mangiferin from Mangifera indica L. Stem Bark using Orthogonal Array Design
Sign Up to like & getrecommendations! Published in 2023 at "Research Journal of Pharmacy and Technology"
DOI: 10.52711/0974-360x.2023.00185
Abstract: A modest and swift microwave-backed extraction process has been established for the abstraction of a flavonoid mangiferin from the Shoot bark of Mangifera indica L. The content in the extracts was quantified by planar chromatography.… read more here.
Keywords: mangiferin; extraction; flavonoid mangiferin; orthogonal array ... See more keywords