An acid-promoted pseudocine substitution manifold of γ-aminocyclopentenone enables divergent access to polycyclic indole derivatives.
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DOI: 10.1039/d1cc06883k
Abstract: We demonstrated γ-aminocyclopentenones to be a suitable surrogate for reactive cyclopentadienone via a pseudocine-substitution manifold. This approach enabled its orchestrated annulation with "tailored" bis-nucleophiles and to furnish complex β,γ-annulated cyclopentanoids or indole-based polycyclic architectures. This… read more here.
Keywords: substitution manifold; promoted pseudocine; pseudocine substitution; manifold aminocyclopentenone ... See more keywords