Exploring genetic interaction manifolds constructed from rich single-cell phenotypes
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aax4438
Abstract: Manifold destiny Mapping of genetic interactions (GIs) is usually based on cell fitness as the phenotypic readout, which obscures the mechanistic origin of interactions. Norman et al. developed a framework for mapping and understanding GIs.… read more here.
Keywords: single cell; cell rna; exploring genetic; genetic interactions ... See more keywords
Four-dimensional manifolds constructed by lens space surgeries of distinct types
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Knot Theory and Its Ramifications"
DOI: 10.1142/s0218216517500699
Abstract: A framed knot with an integral coefficient determines a simply-connected 4-manifold by 2-handle attachment. Its boundary is a 3-manifold obtained by Dehn surgery along the framed knot. For a pair of such Dehn surgeries along… read more here.
Keywords: lens space; knot; four dimensional; manifolds constructed ... See more keywords