Articles with "manipulating epigenome" as a keyword



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Manipulating the epigenome for the treatment of disorders with thrombotic complications.

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Published in 2018 at "Drug discovery today"

DOI: 10.1016/j.drudis.2018.01.004

Abstract: The haemostatic system is tightly regulated to maintain homeostasis to avoid unwanted bleeding or thrombotic complications. Recent research has highlighted the importance of epigenetic changes, such as DNA methylation, histone modifications, and miRNA-based mechanisms, that… read more here.

Keywords: manipulating epigenome; treatment disorders; treatment; thrombotic complications ... See more keywords