Molecular switch manipulating Prelog priority of an alcohol dehydrogenase toward bulky-bulky ketones
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DOI: 10.1016/j.mcat.2019.110741
Abstract: Abstract Structure-guided rational design revealed the molecular switch manipulating the Prelog and anti-Prelog priorities of an NADPH-dependent alcohol dehydrogenase toward prochiral ketones with bulky and similar substituents. Synergistic effects of unconserved residues at 214 and… read more here.
Keywords: prelog; manipulating prelog; switch manipulating; alcohol dehydrogenase ... See more keywords