Genetic manipulation of primary human natural killer cells to investigate the functional and oncogenic roles of PRDM1
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DOI: 10.3324/haematol.2020.254276
Abstract: Extra-nodal natural killer (NK)/T-cell lymphoma, nasal type (ENKTCL) is a highly aggressive lymphoma, in which the tumor suppressor gene PRDM1 is frequently lost or inactivated. We employed two different CRISPR/Cas9 approaches to generate PRDM1-/- primary… read more here.
Keywords: manipulation primary; killer; genetic manipulation; natural killer ... See more keywords