Mannan‐binding lectin attenuates acetaminophen‐induced hepatotoxicity by regulating CYP2E1 expression via ROS‐dependent JNK/SP1 pathway
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Immunology"
DOI: 10.1002/eji.201847830
Abstract: Mannan‐binding lectin (MBL) acts as a soluble pattern recognition molecule in the innate immune system, which is primarily produced by the liver. MBL deficiency occurs with high frequency in the population and is reported to… read more here.
Keywords: binding lectin; induced hepatotoxicity; mbl; expression ... See more keywords
Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin–Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H–Related Protein-5 (FHR5) Deposition
Sign Up to like & getrecommendations! Published in 2018 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2017.11.015
Abstract: Introduction IgA nephropathy (IgAN) is characterized by glomerular deposition of galactose-deficient IgA1 and complement proteins and leads to renal impairment. Complement deposition through the alternative and lectin activation pathways is associated with renal injury. Methods… read more here.
Keywords: binding lectin; iga nephropathy; masp; deposition ... See more keywords
Effect of Optimization of Glycaemic Control on Mannan-Binding Lectin in Type 1 Diabetes
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DOI: 10.1155/2017/1249729
Abstract: Objective Mannan-binding lectin (MBL) concentration in plasma is increased in subjects with type 1 diabetes and associated with increased mortality and risk of diabetic nephropathy. Recent findings show that pancreas transplantation reduces MBL concentration. Whether… read more here.
Keywords: mbl concentration; type diabetes; mannan binding; glycaemic control ... See more keywords
Decreased mannan-binding lectin level in adults with hypopituitarism; dependence on appropriate hormone replacement therapies
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DOI: 10.3389/fimmu.2023.1107334
Abstract: Background Mannan-binding lectin (MBL) is a main component of the lectin pathway of the complement system. Although there are some studies showing links between endocrine and immune systems, the ones concerning hypopituitarism are limited. The… read more here.
Keywords: hypopituitarism; replacement therapies; level; mannan binding ... See more keywords